DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myb and NSI1

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_010309.3	Gene:	NSI1 / 851590	SGDID:	S000002433	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	331	Identity:	68/331 - (20%)
Similarity:	121/331 - (36%)	Gaps:	119/331 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQ----KGQNKSGKTSI--- 75
            |.|.:|:.::.|..|.|......:....|..|...:|::.:......    ..:..:|.|::
Yeast   190 NEDDKENNFNNNSSTLVRIYTDLEGIPNDGSYIKRTPKIPEKDVKSDDLILAPEENNGDTALLRS 254

  Fly    76 ---------GAVHPNYGFGKRWSKSEDVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRW----- 126
                     ||:  ....||:::.||:..|.|.:|   |..:|.|   .|| .|..::.|
Yeast   255 DIVKASVIDGAI--TKSIGKKFTPSEENALDQFIE---EYMKIRG---LDR-RQMCERIWSTDGV 310

  Fly   127 ---------AKVL----NPELIK------------GPWTRDEDDMVIKL-VRNFGPKKWTLIARY 165
                     :|||    ...:.|            |.||.:||..:.:| :...|  .||.:.:.
Yeast   311 IRDGFWANISKVLPYRTRSSIYKHIRRKYHIFEQRGKWTPEEDQELARLCLEKEG--HWTEVGKL 373

  Fly   166 LNGRIGKQCRERWHNHLNPNIKKTA--WTEKEDEI--------IYQAH-------LELGNQ---- 209
            | ||:.:.||:||.|::....|:.:  |:::|:|:        |.:||       ||..|:
Yeast   374 L-GRMPEDCRDRWRNYMKCGSKRGSKRWSKEEEELLTTVVNEMIEEAHQYQRMKALEAANKNDRY 437

  Fly   210 ------------------------WAKIAKRLPG-RTDNAIKNHWNSTM--------------RR 235
                                    |..:::|:.| |:....:..||..:              .|
Yeast   438 NQMYSRGPKGKRISDNPTFKDMINWTVVSERMSGTRSRIQCRYKWNKLVTDEAARSMLSIPVSER 502

  Fly   236 KYDVER 241
            |:.:||
Yeast   503 KWLLER 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	17/64 (27%)
		Myb_DNA-bind_6	88..147	CDD:290632	21/88 (24%)
		SANT	136..184	CDD:197842	18/60 (30%)
		Myb_DNA-bind_6	139..197	CDD:290632	19/60 (32%)
		SANT	188..235	CDD:197842	15/106 (14%)
		Myb_DNA-binding	188..233	CDD:278669	15/90 (17%)
		Cmyb_C	388..530	CDD:286408
NSI1	NP_010309.3	REB1	53..567	CDD:227476	68/331 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344735
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2047
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860