DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myb and MYB64

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_196666.1	Gene:	MYB64 / 830972	AraportID:	AT5G11050	Length:	423	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	136/535 - (25%)
Similarity:	226/535 - (42%)	Gaps:	176/535 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSE 92
            :||  .:|.|..:::        :|.|.::.::....:.:||.          |..||.|..|:.
plant    30 KNE--ALCFKKQERS--------IDRPIVKTTRAIEIRNENKE----------NMMFGPRKEKNL 74

  Fly    93 DVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPK 157
            .|:.:.:|:...:::..     ||..::|..:        .:|||.||.|||..:||||...|.:
plant    75 AVIGEIVVKGAAKDYTC-----KDITKKQPYK--------NIIKGQWTADEDRKLIKLVMQHGER 126

  Fly   158 KWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTD 222
            ||.:|:..|.||.||||||||||||.|:|||.:|:|:|:.::.:||..:||:||:|||.:.|||:
plant   127 KWAVISEKLEGRAGKQCRERWHNHLRPDIKKDSWSEEEERLLVEAHTRIGNKWAEIAKLIQGRTE 191

  Fly   223 NAIKNHWNSTMRRKYD--VERRSVNA-SGSDL-----KSSRTHLITLIKSGGISKCMNNMQHNKE 279
            |:||||||:|.||:..  ..:||.|| |.||:     .:.|..:        :...:.|:::|.:
plant   192 NSIKNHWNATKRRQNSKRKHKRSKNADSNSDIDDLSPSAKRPRI--------LEDYIKNIENNDK 248

  Fly   280 SGGEAVNKSENADGASVTAVKGGDLAQESQDDHQKGSNLAHLSMQHLIKLTMPRQTPIILKRTRK 344
            :.||           ::....|.::...|..|.
plant   249 NNGE-----------NIMTTSGNNVLSTSNYDQ-------------------------------- 270

  Fly   345 HIPETHHQAGCSSSETFNQEEAAGNARSRPPSSPVISPIKSLPFSPSHFLKSPCLT-TFEDMDLR 408
                            ||.|::..:....|....::            |||:.... :.|:::|.
plant   271 ----------------FNSEDSTSSLLDDPYDEELV------------FLKNIFENHSLENINLS 307

  Fly   409 ASTPVTKVYNRVGMEIKKEMETSS---IETPHKSQLGPRTPTP------FKKALAAIGKKRDGRR 464
            ..|.:|:             .:||   ||.|        .|.|      |...|.|:..
plant   308 QGTEITQ-------------SSSSGFMIENP--------KPKPNLYNNTFGTHLGAMVT------ 345

  Fly   465 YEPSSPSSLVED--LAEIIHEEHLSNS----LTANNSKMMGAADQNSTLSTEYNAQSPPHMKRAR 523
             ||::.|.|..|  |:::::....|:|    |::||::..|   :|..|..:.|:.|    :|..
plant   346 -EPANSSHLASDIYLSDLLNGTASSSSSLTFLSSNNNEHAG---ENELLLPQANSTS----ERRE 402

  Fly   524 KSLL-----STWSSN 533
            ..|:     ||..||
plant   403 MDLIEMLSGSTQGSN 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	8/46 (17%)
		Myb_DNA-bind_6	88..147	CDD:290632	14/58 (24%)
		SANT	136..184	CDD:197842	30/47 (64%)
		Myb_DNA-bind_6	139..197	CDD:290632	35/57 (61%)
		SANT	188..235	CDD:197842	24/46 (52%)
		Myb_DNA-binding	188..233	CDD:278669	23/44 (52%)
		Cmyb_C	388..530	CDD:286408	36/162 (22%)
MYB64	NP_196666.1	PLN03091	105..>209	CDD:215570	59/103 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000329
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45614
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.870