DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myb and MYB33

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_001078537.1	Gene:	MYB33 / 830497	AraportID:	AT5G06100	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	125/492 - (25%)
Similarity:	198/492 - (40%)	Gaps:	138/492 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 QQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLN-GRIGKQCRERWHNHLNPNI 186
            :.||.   ...|.||||:..|||::|..|...|...|..:.::.: .|.||.||.||.|||.||:
plant    24 RSRWD---GHALKKGPWSSAEDDILIDYVNKHGEGNWNAVQKHTSLFRCGKSCRLRWANHLRPNL 85

  Fly   187 KKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASGSDL 251
            ||.|::::|:::|.:.|.::||:||::|..|||||||.|||:||:.::|:        ..:|..|
plant    86 KKGAFSQEEEQLIVELHAKMGNRWARMAAHLPGRTDNEIKNYWNTRIKRR--------QRAGLPL 142

  Fly   252 KSSRTHLITLIKSGGISK------------------CMNNMQHNKESGGEAVNKSENADG----A 294
            .....|:..|..|...:|                  |.:|:..      :.:|.::...|    |
plant   143 YPPEMHVEALEWSQEYAKSRVMGEDRRHQDFLQLGSCESNVFF------DTLNFTDMVPGTFDLA 201

  Fly   295 SVTAVKGGDLAQESQDDHQKGSNLAHLSMQHLIKLTMPR----QTPIILKRTRKHIPETHHQAGC 355
            .:||.|                |:.:.:       :.||    .||.|....|....|..: .||
plant   202 DMTAYK----------------NMGNCA-------SSPRYENFMTPTIPSSKRLWESELLY-PGC 242

  Fly   356 SSSETFNQE-EAAGNARSRPPSSPVISPIKSLPFSPSHFL----KSPCLTTFEDMDLRASTPVTK 415
            ||  |..|| .:....|:..|.:...:...|:|....|.|    .||.:............|.:|
plant   243 SS--TIKQEFSSPEQFRNTSPQTISKTCSFSVPCDVEHPLYGNRHSPVMIPDSHTPTDGIVPYSK 305

  Fly   416 -VYNRVGMEIK--KEMETS------SIETPHKSQLGP-----RTPTPFKKALAAIGKKRDGRRYE 466
             :|..|.:|:.  :..||:      |...||...|.|     ::|.|     ...|::.|   ..
plant   306 PLYGAVKLELPSFQYSETTFDQWKKSSSPPHSDLLDPFDTYIQSPPP-----PTGGEESD---LY 362

  Fly   467 PSSPSSLVEDLAEIIHEEHLSNSLTANN----------SKMMGAADQNSTLSTEY---------- 511
            .:..:.|::.|   :.|..:.|:.|.||          |..:|....:.|.|.|:
plant   363 SNFDTGLLDML---LLEAKIRNNSTKNNLYRSCASTIPSADLGQVTVSQTKSEEFDNSLKSFLVH 424

  Fly   512 ------NA-QSPPHMK-RARKSLL----------STW 530
                  || ::||..: :.||.||          |:|
plant   425 SEMSTQNADETPPRQREKKRKPLLDITRPDVLLASSW 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	2/8 (25%)
		Myb_DNA-bind_6	88..147	CDD:290632	10/23 (43%)
		SANT	136..184	CDD:197842	21/48 (44%)
		Myb_DNA-bind_6	139..197	CDD:290632	24/58 (41%)
		SANT	188..235	CDD:197842	22/46 (48%)
		Myb_DNA-binding	188..233	CDD:278669	22/44 (50%)
		Cmyb_C	388..530	CDD:286408	41/197 (21%)
MYB33	NP_001078537.1	PLN03091	32..>137	CDD:215570	48/112 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770