DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myb and MYB3R-3

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_001327447.1	Gene:	MYB3R-3 / 820094	AraportID:	AT3G09370	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	611	Identity:	169/611 - (27%)
Similarity:	252/611 - (41%)	Gaps:	168/611 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASASTENGEELMNYGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTGQK 65
            |.....|.||..:         |.:..||:.:......|....:|.|.:  .||.:. |..|...
plant    23 MMDLQEETGEVKI---------EDQCVENKQSTPASCSSVSEGSAGSSH--KSPTIA-SPATVSP 75

  Fly    66 GQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVET-HGENWEIIGPHFKDRLEQQVQQRWAKV 129
            .....|:|| |.:....|   .|:..||..|:|.|:| .|::|:.|...|.||.|.|...||.||
plant    76 THRYLGRTS-GPIRRAKG---GWTPEEDETLRQAVDTFKGKSWKNIAKSFPDRTEVQCLHRWQKV 136

  Fly   130 LNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWTEK 194
            |||:|||||||.:||:.:::||..:||.||::||:.|.|||||||||||||||||:|.|.|||.:
plant   137 LNPDLIKGPWTHEEDEKIVELVEKYGPAKWSIIAQSLPGRIGKQCRERWHNHLNPDINKDAWTTE 201

  Fly   195 EDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYD------------VERRSVNAS 247
            |:..:..||...||:||:|||.|||||||||||||||::::|.:            ..|..|..|
plant   202 EEVALMNAHRSHGNKWAEIAKVLPGRTDNAIKNHWNSSLKKKSEFYLLTGRLPPPTTTRNGVPDS 266

  Fly   248 GSDLKSSRTHLI--TLIKSGGISKCMNNMQHNKESGGEAVNKS---ENADGAS-VTAVKGGDLAQ 306
            .:...||....:  ::.::..::..:||:   .|.|...:|.|   |....|| :|::  .:.|:
plant   267 VTKRSSSAQKRVFGSVAQTSSVTTDVNNL---AEDGNGQINSSVPVEEVVAASRMTSL--NEYAR 326

  Fly   307 ESQDDHQKGSNLAHLSMQHLIKLTMPRQTPIILKRTRKHIPETHHQAG-------------CSSS 358
            ..|                     :|...|         :||....|.             ..:|
plant   327 SPQ---------------------LPNPEP---------LPENGGAANNGYHLYYTPQIDYYRAS 361

  Fly   359 ETFNQEEAAGNARSRPPSSPVISPIKSLPFSPSHFLKSPCLTTFEDMDLRASTPVTKVYNRVGME 423
            |...|..........|.:|||           |.|...||
plant   362 EVDTQRMYGNECGCSPSASPV-----------SFFTPPPC------------------------- 390

  Fly   424 IKKEMETSSIETPHKSQLGPRTPTPFKKALAAIGKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSN 488
                      ...|.:...||:|..:        .:..||.| |::||...:....::.:::
plant   391 ----------RNVHSNGSTPRSPESY--------LREAGRTY-PNTPSIFRKRRPRVVVQDN--- 433

  Fly   489 SLTANNSKMMGAA---DQ-----------NSTLSTEYNAQSPPHMKRARKSLLSTWSSNHPYNAG 539
                ||:|....|   ||           .:..|..||. |||:..|::::.:        :.:.
plant   434 ----NNAKKTDEAKEVDQKVNDGKDSSEIQNNGSNAYNL-SPPYRIRSKRTAV--------FKSR 485

  Fly   540 SAKRIQPFETETPSKFLTSPGDILKD 565
            ..:.|...|.:...:..:|..|:|.|
plant   486 QLEFISREEEKADDETKSSEKDMLID 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	20/47 (43%)
		Myb_DNA-bind_6	88..147	CDD:290632	31/59 (53%)
		SANT	136..184	CDD:197842	31/47 (66%)
		Myb_DNA-bind_6	139..197	CDD:290632	36/57 (63%)
		SANT	188..235	CDD:197842	29/46 (63%)
		Myb_DNA-binding	188..233	CDD:278669	29/44 (66%)
		Cmyb_C	388..530	CDD:286408	27/155 (17%)
MYB3R-3	NP_001327447.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	100	1.000	Domainoid score	I2357
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000329
OrthoInspector	1	1.000	-	-		otm2880
orthoMCL	1	0.900	-	-		OOG6_100129
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1086
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.670