DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myb and MYB88

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_001030957.1	Gene:	MYB88 / 814812	AraportID:	AT2G02820	Length:	484	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	111/528 - (21%)
Similarity:	202/528 - (38%)	Gaps:	125/528 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 WTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWTEKEDEIIYQAH 203
            |:.:|||::.|.:...|.:.|.:||...|.:..:|||.||:.:||.:.|:..|:.:||.::.:|.
plant    33 WSPEEDDILRKQISLQGTENWAIIASKFNDKSTRQCRRRWYTYLNSDFKRGGWSPEEDTLLCEAQ 97

  Fly   204 LELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASGSDLKSSRTHLITLIKSGGIS 268
            ...||:|.:|||.:.||||||:||.:.:..:::...|                   .:.|...|:
plant    98 RLFGNRWTEIAKVVSGRTDNAVKNRFTTLCKKRAKHE-------------------AMAKENRIA 143

  Fly   269 KCMNNMQHNKESGGEAVNKSEN-----ADGASVTAVKGGDLAQESQDDHQKGSNLAHL------- 321
            .|:|               |:|     .||.|.      .|..||:....|....:|:
plant   144 CCVN---------------SDNKRLLFPDGIST------PLKAESESPLTKKMRRSHIPNLTEIK 187

  Fly   322 ---SMQHL-IKLTMPRQTPIILKRTRKH-IPETHHQAGCSSSETFNQEEAAGNARSRPPSSPVIS 381
               ...|: ::.||.:|        |:| .....|.|  :||:...:::..||.:......
plant   188 SYGDRSHIKVESTMNQQ--------RRHPFSVVAHNA--TSSDGTEEQKQIGNVKESDGED---- 238

  Fly   382 PIKSLPFSPSHFLKSPCLTTFEDMDLRASTPVTKVYNRVGMEIKKEMETSSIETPHKSQLGPRTP 446
              ||   :...|||.      :|..:.|.....::.:.:..::..:....|:|...|
plant   239 --KS---NQEVFLKK------DDSKVTALMQQAELLSSLAQKVNADNTDQSMENAWK-------- 284

  Fly   447 TPFKKALAAIGKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSNSLTANNSKMMGAADQNSTLSTEY 511
              ..:......|:.|..||........:::..:::.:...||..:.::.:.....|  |..|:||
plant   285 --VLQDFLNKSKENDLFRYGIPDIDFQLDEFKDLVEDLRSSNEDSQSSWRQPDLHD--SPASSEY 345

  Fly   512 NAQS--------PPHMKRARKSLLSTWSSNHPYNAGSAKR---IQPFETETPSKFLTSPGDILKD 565
            ::.|        .|...:.::.:..|.:::|..|.|...:   |....|......|::..|:||:
plant   346 SSGSGSGSTIMTHPSGDKTQQLMSDTQTTSHQQNGGELLQDNGIVSDATVEQVGLLSTGHDVLKN 410

  Fly   566 TLCSEQDLPFDEGRKENRPFHNRRINKYRGGLTYDHVIDPKWARVACGKSRDQMFMEEQAYACLK 630
               |.:.:|.....:.|.|..                :.|.:..:|.|....| |.|.:....||
plant   411 ---SNETVPIPGEEEFNSPVQ----------------VTPLFRSLAAGIPSPQ-FSESERNFLLK 455

  Fly   631 NLSCISRS 638
            .|...|.|
plant   456 TLGVESPS 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842
		Myb_DNA-bind_6	88..147	CDD:290632	4/7 (57%)
		SANT	136..184	CDD:197842	16/44 (36%)
		Myb_DNA-bind_6	139..197	CDD:290632	20/57 (35%)
		SANT	188..235	CDD:197842	18/46 (39%)
		Myb_DNA-binding	188..233	CDD:278669	18/44 (41%)
		Cmyb_C	388..530	CDD:286408	21/149 (14%)
MYB88	NP_001030957.1	SANT	24..>141	CDD:333364	38/126 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810