Protein Alignment Myb and MYB

DIOPT Version :10

• Sequence 1: NP_511170.1
• Gene: Myb / 32543
• FlyBaseID: FBgn0002914
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_054211496.1
• Gene: MYB / 4602
• HGNCID: 7545
• Length: 994
• Species: Homo sapiens
• Alignment Length: 837
• Identity: 239/837 - (28%)
• Similarity: 333/837 - (39%)
• Gaps: 298/837 - (35%)

  Fly     1 MASASTENGEELMN--YGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTG 63
            :|.||..:...::.  |.|:.|        :||.::||.|      .|...|
Human   230 LARASVNSAGIILTSIYSSDED--------DEDFEMCDHD------YDGLLP------------- 267

  Fly    64 QKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHG-ENWEIIGPHFKDRLEQQVQQRWA 127
                 ||||..:|..        ||::.||..||:|||.:| ::|::|..:..:|.:.|.|.||.
Human   268 -----KSGKRHLGKT--------RWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQ 319

  Fly   128 KVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWT 192
            |||||||||||||::||..||:||:.:|||:|::||::|.|||||||||||||||||.:|||:||
Human   320 KVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWT 384

  Fly   193 EKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVE---RRSVNASGSDLKSS 254
            |:||.||||||..|||:||:|||.||||||||||||||||||||.:.|   :.|..||...:.:|
Human   385 EEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVATS 449

  Fly   255 ---RTHLITLIKSG--------------------GISKCMN-------------NMQHNKESGGE 283
               .:||:...::.                    .||:..|             |:.:..:....
Human   450 FQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAA 514

  Fly   284 AVNKSEN-ADGASVTAVKGGDLAQESQDDHQKGSNLAHLSMQHLIKLTMPRQTPIILKRTRKH-- 345
            |:.:..| .|......:|..:|...|.::..||..    :..|.........| .|...||.|
Human   515 AIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQ----TQNHTCSYPGWHST-TIADHTRPHGD 574

  Fly   346 ----------------------IPETH---------HQ-------------------------AG 354
                                  :||..         ||                         :.
Human   575 SAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSDSSSW 639

  Fly   355 C--SSSETF-----------------------NQEEAAGNARSR-----------------PP-- 375
            |  ||.|.|                       |..:.||....|                 ||
Human   640 CDLSSFEFFEEADFSPSQHHTGKALQLQQREGNGTKPAGEPSPRVNKRMLSESSLDPPKVLPPAR 704

  Fly   376 ----------------------------------SSPVISPIKSLPFSPSHFLKSPCLTTFEDMD 406
                                              |:|..||:||||||||.||.:.  :..|:.|
Human   705 HSTIPLVILRKKRGQASPLATGDCSSFIFADVSSSTPKRSPVKSLPFSPSQFLNTS--SNHENSD 767

  Fly   407 LR----ASTP-------VTKVYNRVGMEIKKEMETSSIETP--HKSQL--GPRTPTPFKKALAAI 456
            |.    .|||       ||..::| ...:|.:.|.:...||  .:|.|  .||||||||.||||.
Human   768 LEMPSLTSTPLIGHKLTVTTPFHR-DQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQ 831

  Fly   457 GKKRDGRRYEPSSPSSLVEDLAEIIHEEHLSNSLTANNSKMMGAADQNSTLSTEYNAQSPPHMKR 521
            ..|....:..|.:||.|||||.::|.:|                 ...|.:..|:....||.:|:
Human   832 EIKYGPLKMLPQTPSHLVEDLQDVIKQE-----------------SDESGIVAEFQENGPPLLKK 879

  Fly   522 ARKSLLS------TWSSNHPYNAGSAKRIQPFETETP---------SKFLTSPGDILKDTLCSEQ 571
            .::.:.|      .:..:|.:. |.:...|.|...:|         |..|.:|....:|.:....
Human   880 IKQEVESPTDKSGNFFCSHHWE-GDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVLKAF 943

  Fly   572 DLPFDEGRKENRPFHNRRINKYRGGLTYDHVIDP---KWARVACGKSRDQMFMEEQA 625
            .:|      :||...:              .:.|   .|...:|||..:||....||
Human   944 TVP------KNRSLAS--------------PLQPCSSTWEPASCGKMEEQMTSSSQA 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	Myb_DNA-bind_6	88..147	CDD:372817	31/59 (53%)
		PLN03212	136..>236	CDD:178751	75/99 (76%)
		Cmyb_C	388..>484	CDD:462753	43/110 (39%)
MYB	XP_054211496.1	SANT	276..324	CDD:197842	20/55 (36%)
		REB1	325..>438	CDD:227476	81/112 (72%)
		LMSTEN	504..549	CDD:462332	9/44 (20%)
		Cmyb_C	751..910	CDD:462753	53/179 (30%)