DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myb and ttf1.6

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	XP_005168698.1	Gene:	ttf1.6 / 449954	ZFINID:	ZDB-GENE-041008-214	Length:	549	Species:	Danio rerio

Alignment Length:	322	Identity:	68/322 - (21%)
Similarity:	114/322 - (35%)	Gaps:	96/322 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ENGEELMNYGSNSDSEESEYSENED-----TQVCD-----------KDSQQNSNADSGYP----- 50
            :.|.|| .:|..|.:|.....:|..     |.|.|           |:||..:|....|.
Zfish   205 KQGIEL-RHGRFSTAENERLRQNVSNFLALTGVKDAIKLFHPKRFPKESQTLANLKRKYSFFVKI 268

  Fly    51 ---LDSPELQDSKTTGQK---GQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHGENWEI 109
               :..| ..|..|.|.|   .:||.|               .:::.|:..|.:....:|.:|:.
Zfish   269 AEGIPRP-CHDVYTRGTKIYDDRNKKG---------------NFTEEEEKSLLKYYTLYGPDWKK 317

  Fly   110 IGPHFKDRLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQC 174
            |... .||....:::|::.:   ..|:||||.:|...:::.||:.       :...|..
Zfish   318 ISDK-TDRSSYSLEKRFSHL---SKIRGPWTTNEVQRLLRAVRDH-------VVSVLKS------ 365

  Fly   175 RERWHNHLNPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDV 239
                   .||..||.....:  ||:|||     ..|:|||:::..|.....::.|.|.:..:..
Zfish   366 -------ANPKKKKPKRVSR--EILYQA-----LPWSKIAEKVKTRCWTKCRDKWMSILASRMS- 415

  Fly   240 ERRSVNASGSDLKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENADGASVTAVKG 301
              ..:...|...:.::..||         :.|..||         |....:.|...:|||.|
Zfish   416 --SGITFRGRKAQEAKIKLI---------RAMYEMQ---------VEDVVDVDWEHLTAVFG 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	8/46 (17%)
		Myb_DNA-bind_6	88..147	CDD:290632	14/58 (24%)
		SANT	136..184	CDD:197842	8/47 (17%)
		Myb_DNA-bind_6	139..197	CDD:290632	10/57 (18%)
		SANT	188..235	CDD:197842	13/46 (28%)
		Myb_DNA-binding	188..233	CDD:278669	13/44 (30%)
		Cmyb_C	388..530	CDD:286408
ttf1.6	XP_005168698.1	Myb_DNA-bind_6	296..351	CDD:290632	14/58 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900