Protein Alignment Myb and Mybl1

DIOPT Version :10

• Sequence 1: NP_511170.1
• Gene: Myb / 32543
• FlyBaseID: FBgn0002914
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_038965321.1
• Gene: Mybl1 / 297783
• RGDID: 1306940
• Length: 774
• Species: Rattus norvegicus
• Alignment Length: 846
• Identity: 239/846 - (28%)
• Similarity: 340/846 - (40%)
• Gaps: 287/846 - (33%)

  Fly     3 SASTENGEELMN----YGSNSDSEESEYSENEDTQVCDKDSQQNSNADSGYPLDSPELQDSKTTG 63
            |.|.:|...|..    :|.......|| .|::|.|..|.|            .:.|:
  Rat     5 SRSRDNQNCLQTVAHIFGGMETGPHSE-DEDDDLQYADHD------------YEVPQ-------- 48

  Fly    64 QKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHG-ENWEIIGPHFKDRLEQQVQQRWA 127
            |||..|....            .:|::.||..||:|||.|| ::|.:|..|.::|.:.|.|.||.
  Rat    49 QKGLKKLWNR------------VKWTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQ 101

  Fly   128 KVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTAWT 192
            |||||||||||||::||..||:||:.:|||:|:|||::|.|||||||||||||||||.:||::||
  Rat   102 KVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGRIGKQCRERWHNHLNPEVKKSSWT 166

  Fly   193 EKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASGSDLKSSR-- 255
            |:||.|||:||..|||:||:|||.|||||||:||||||||||||.:.|....:...|:..||:
  Rat   167 EEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSERSSSKLQ 231

  Fly   256 -------THLIT----------------------------------------------------- 260
                   .||.|
  Rat   232 HKPCATMDHLQTQNQFYIPVQIPGYQYVSPDGNCVEHVQTSAFIQQPFVDEDPDKEKKIKELELL 296

  Fly   261 --------------------------LIKSGGISKCMNNM-QHNKE----SGGEAVNKSEN---- 290
                                      .:....:|..:||: :|..|    ...:.|:..:|
  Rat   297 LMSAENEVRRKRLPPQPGSFSSWSGSFLMDDSMSNTLNNLEEHTTEFYSMDENQTVSAQQNSPTK 361

  Fly   291 ---------------------------ADGASVTAVKGGDLAQESQD------------DHQKG- 315
                                       :|..:.:.|...||:..:..            .|.:|
  Rat   362 FLAVEANAVLSSLQTIPEFAETLELIESDPVAWSDVTSFDLSDAAASPVKSTPVKLMRIQHNEGA 426

  Fly   316 ----------------------SNLAHLSMQHLIKLTMPRQTPIIL-KRTRKHIPETHHQAGCSS 357
                                  |....|:..:::|.:.|   |.|| |:.|..:.::   ||...
  Rat   427 MECQFNVSLVLEGKKNSCNGGDSEAIPLASPNVVKFSTP---PTILRKKKRLRVGQS---AGSEL 485

  Fly   358 SETFNQEEAAGNARSRPPSSPVISPIKSLPFSPSHF-----------LKSPCLTTFEDMDLRAST 411
            .|....|  ..||..:.      :|:|:||||||.|           :::|..|         ||
  Rat   486 GEGSLSE--GNNAALKH------TPVKTLPFSPSQFFNTCPGSEQLNIENPSFT---------ST 533

  Fly   412 PVTKVYNRVGMEIKKE------METSSIETP--HKSQLG--PRTPTPFKKALAAIGKKRDGRRYE 466
            |:......:...::||      .|.....||  .:|.||  ||||||||.||||..||     |.
  Rat   534 PICGQKVLITTPLQKEATPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKK-----YG 593

  Fly   467 P----SSP-SSLVEDLAEIIHEEHLSNSLTANNSKMMGAADQNS--TLSTEYNAQSPPHMKRARK 524
            |    |.| :.|.||:.|::.||       ......:...|:.:  :...|::|.    :|:.||
  Rat   594 PLKIVSQPLAFLEEDIREVLKEE-------TGTDIFLKEEDEPAYKSCKQEHSAS----VKKVRK 647

  Fly   525 SL-LSTWSSNHPYNAGSAKRIQPFETET--PSKFLTSPGDILKDTLCS----EQDLPFDEGRK-- 580
            || |.:|....|......:.|...::|.  .:..|..|...:.|..|:    :||:  :...|
  Rat   648 SLALESWDKEEPGTQLLTEDISDMQSENILTTSLLMIPLLEIHDNRCNLTPEKQDI--NSANKTY 710

  Fly   581 ---ENRPFHNR-RINKYRGGLTYDHVIDPKWARVACGKSRDQMFMEEQAYACLKNL---SCISRS 638
               :.||..|. :..|....|.    .:.:|..|..||:.||:.|.|||...|...   |..||:
  Rat   711 TLTKKRPNPNTCKAVKLEKSLQ----SNCEWETVVYGKTEDQLIMTEQARRYLSTYTAPSSTSRA 771

  Fly   639 L 639
            |
  Rat   772 L 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	Myb_DNA-bind_6	88..147	CDD:372817	33/59 (56%)
		PLN03212	136..>236	CDD:178751	73/99 (74%)
		Cmyb_C	388..>484	CDD:462753	40/121 (33%)
Mybl1	XP_038965321.1	Myb_DNA-bind_6	61..121	CDD:372817	33/59 (56%)
		PLN03091	107..>215	CDD:215570	78/107 (73%)
		LMSTEN	263..308	CDD:462332	0/44 (0%)
		Cmyb_C	508..664	CDD:462753	53/180 (29%)