Protein Alignment Myb and Mybl2

DIOPT Version :10

• Sequence 1: NP_511170.1
• Gene: Myb / 32543
• FlyBaseID: FBgn0002914
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001417114.1
• Gene: Mybl2 / 296344
• RGDID: 1308474
• Length: 705
• Species: Rattus norvegicus
• Alignment Length: 762
• Identity: 219/762 - (28%)
• Similarity: 312/762 - (40%)
• Gaps: 242/762 - (31%)

  Fly    51 LDSPELQDSKTTGQKGQNKSGKTSIGAVHPNYGFGKRWSKSEDVLLKQLVETHG-ENWEIIGPHF 114
            ||....||  |.....:.:..|..:           :|:..||.||:.||...| ::|:.:..||
  Rat    10 LDELRYQD--TDSDLLEQRDNKCKV-----------KWTHEEDELLRALVRQFGQQDWKFLASHF 61

  Fly   115 KDRLEQQVQQRWAKVLNPELIKGPWTRDEDDMVIKLVRNFGPKKWTLIARYLNGRIGKQCRERWH 179
            .:|.:||.|.||.:||||:|:|||||::||..||:||:.:|.|:|||||::|.||:|||||||||
  Rat    62 PNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWH 126

  Fly   180 NHLNPNIKKTAWTEKEDEIIYQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDV----- 239
            |||||.:||:.|||:||.||.:||..|||:||:|||.||||||||:|||||||::||.|.
  Rat   127 NHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPN 191

  Fly   240 ERRS---------------------VNASGS---------------------------------- 249
            |.|.                     |...||
  Rat   192 ESRDCKPVYLLLELEDKDYQQNVQPVEGPGSLVSSWPLAPSTVKEEESSEEEAAVATTSKEHKQE 256

  Fly   250 ----DL------------------------------------------KSSRTHLITLIKSGGIS 268
                ||                                          :||.:..:.||:|...:
  Rat   257 PVPTDLGEVRTPEPLEFLKREYQEESSPETSLPYKWVVEAANLLIPAVESSLSEALDLIESDPDA 321

  Fly   269 KC-MNNMQHNKESGGE-AVNKS-------------ENADGASVTAVKGGDLAQESQDDHQKGSNL 318
            .| ::.....:|...| :||.|             :.|......|..|..:.:...|.|.. |:|
  Rat   322 WCDLSKFDLPEEPSAEGSVNSSPVQLQTPQQQQQHQQALSFHQAATPGPSVTEYRLDGHTI-SDL 385

  Fly   319 AHLSMQHLIKLTMPRQ--------TPIILKRTRKH----IPETHHQAGCSSSETFNQEEAAGNAR 371
            :..|...||.::...:        .|.:|||.:|.    .|.|.:.|..|..::.|
  Rat   386 SRSSRGELIPISPSTEFGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCN--------- 441

  Fly   372 SRPPSSPVISPIKSLPFSPSHF-----------LKSPCLTTFEDMDLRASTPV------------ 413
            |..|.|   :|:|:||||||.|           |:||.||         ||||
  Rat   442 SLTPKS---TPVKTLPFSPSQFLNFWNKQDTLELESPSLT---------STPVCSQKVVVTTPLH 494

  Fly   414 ---TKVYNRVGME-IKKEMETSSIETPHKSQLGPRTPTPFKKALAAIGKKRDGRRYEPSSP---- 470
               |.::.:.... :..:.:.|...|||       ||||||.||         .:|.|..|
  Rat   495 RDKTPLHQKYPSRFVTPDQKYSMDNTPH-------TPTPFKNAL---------EKYGPLKPLPQT 543

  Fly   471 SSLVEDLAEIIHEEH-----LSNSLTANNSKMMGAADQNSTLSTEYNAQSPPHMKRARKSL-LST 529
            ..|.|||.|::..|.     :.:.:.....|.....           .:||  :|:.|||| |..
  Rat   544 PHLEEDLKEVLRSEAGIELIIEDDMRPEKQKRKPGL-----------RRSP--IKKVRKSLALDI 595

  Fly   530 WSSNHPYNAGSAKRIQPFETETPSKFLTSPGDILKDTLCSEQDLPFDEGRKENRPFHNRRINKYR 594
            ...:....:.::.:.....|..||   :|.|.||..  ..|.:...::|..:.:|.......|.|
  Rat   596 VDEDGKMMSSTSPKTLSLPTSVPS---SSSGFILPG--IKEDNSLLNQGFLQAKPEKVVATQKPR 655

  Fly   595 GGLTYDHVIDPKWARVACGKSRDQMFMEEQAYACLKNL--SCISRSL 639
            ..:.....:...|..||||.::||:||:|:|...|..|  |..||:|
  Rat   656 SHIPAPAPMTRAWKTVACGGTKDQLFMQEKARQLLGRLKSSHTSRTL 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	Myb_DNA-bind_6	88..147	CDD:372817	29/59 (49%)
		PLN03212	136..>236	CDD:178751	69/99 (70%)
		Cmyb_C	388..>484	CDD:462753	35/126 (28%)
Mybl2	NP_001417114.1	None