DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myb and rtf1

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_594730.2	Gene:	rtf1 / 2541545	PomBaseID:	SPAC22F8.07c	Length:	466	Species:	Schizosaccharomyces pombe

Alignment Length:	237	Identity:	51/237 - (21%)
Similarity:	97/237 - (40%)	Gaps:	62/237 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 RWSKSEDVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRWAKVLNP-ELIKGPWTRDEDDMVIKL 150
            :|:..::..||:|||.||.:|.:|| ...:||....:..|...:.| |:.:.|||..|.:.:||.
pombe   258 KWTIEDEAELKKLVEKHGTSWSLIG-KLSNRLPMHCRDHWRDYIQPGEINRSPWTIQEKEKLIKT 321

  Fly   151 VRNF------GPKKWTLIARYLNGRIGKQCRERWHNHLNPNIKKTA--------W--------TE 193
            |..:      .|.:|:||::.:..|....||.:::..::.:|..::        |        ..
pombe   322 VNQYLQSNPSSPIQWSLISKNMRNRHRHHCRWKYYTLISRDIHNSSPFKLGDSIWLIERMMDLNV 386

  Fly   194 KEDEII-------YQAHLELGNQWAKIAKRLPGRTDNAIKNHWNSTMRRKYDVERRSVNASG-SD 250
            .|:.:|       |..||     |          |.:|.|:|        ::..::::...| |.
pombe   387 AEERMIDWKCLSEYANHL-----W----------TADACKSH--------FERIKKTLFIDGLST 428

  Fly   251 LKSSRTHLITLIKSGGISKCMNNMQHNKESGGEAVNKSENAD 292
            ...:..||..::.|......::|:.       ::.....|||
pombe   429 FSDTLIHLHKMLNSSPEETYISNLH-------DSYTAFSNAD 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	14/44 (32%)
		Myb_DNA-bind_6	88..147	CDD:290632	20/59 (34%)
		SANT	136..184	CDD:197842	14/53 (26%)
		Myb_DNA-bind_6	139..197	CDD:290632	16/79 (20%)
		SANT	188..235	CDD:197842	11/69 (16%)
		Myb_DNA-binding	188..233	CDD:278669	11/67 (16%)
		Cmyb_C	388..530	CDD:286408
rtf1	NP_594730.2	REB1	1..466	CDD:227476	51/237 (22%)
		Myb_DNA-bind_6	259..318	CDD:290632	20/59 (34%)
		Myb_DNA-binding	307..359	CDD:278669	14/51 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100129
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2047
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830