DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myb and reb1

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_001342963.1	Gene:	reb1 / 2539930	PomBaseID:	SPBC1198.11c	Length:	504	Species:	Schizosaccharomyces pombe

Alignment Length:	148	Identity:	40/148 - (27%)
Similarity:	66/148 - (44%)	Gaps:	19/148 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 WSKSEDVLLKQLVETHGENWEIIGPHFKDRLEQQVQQRWAKVL--NPELIKGPWTRDEDDMVIKL 150
            |||.||..|::.|..||:.|..||.... |:....:.||..|:  ..:|.:..|:.:|:..::::
pombe   316 WSKEEDEELRKNVVEHGKCWTKIGRKMA-RMPNDCRDRWRDVVRFGDKLKRNAWSLEEETQLLQI 379

  Fly   151 VRNFGPKK-------WTLIARYLNGRIGKQCRERWHNHLNP----NIKKTAWTEKEDEIIYQAHL 204
            |.....::       |||:|:.|..|...|||.::......    .:::..|..   |.||.:.|
pombe   380 VAELRNREDLSSDINWTLVAQMLGTRTRLQCRYKFQQLTKAASKFELQENVWLL---ERIYDSLL 441

  Fly   205 ELGNQ--WAKIAKRLPGR 220
            ..|.:  |..|.|...||
pombe   442 NNGGKIHWENIVKEANGR 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	16/45 (36%)
		Myb_DNA-bind_6	88..147	CDD:290632	19/60 (32%)
		SANT	136..184	CDD:197842	12/54 (22%)
		Myb_DNA-bind_6	139..197	CDD:290632	13/68 (19%)
		SANT	188..235	CDD:197842	11/35 (31%)
		Myb_DNA-binding	188..233	CDD:278669	11/35 (31%)
		Cmyb_C	388..530	CDD:286408
reb1	NP_001342963.1	REB1	2..504	CDD:227476	40/148 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2047
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930