DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myb and Dmtf1l

DIOPT Version :9

Sequence 1:	NP_511170.1	Gene:	Myb / 32543	FlyBaseID:	FBgn0002914	Length:	657	Species:	Drosophila melanogaster
Sequence 2:	NP_808373.1	Gene:	Dmtf1l / 237029	MGIID:	3045322	Length:	470	Species:	Mus musculus

Alignment Length:	275	Identity:	66/275 - (24%)
Similarity:	112/275 - (40%)	Gaps:	69/275 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 KGQNKS--GKTSIGAVHPNYGFGKR-------------WSKSEDVLLKQLVETHGENWEIIGPHF 114
            ||:.|.  ...|:|...|.:...:|             :|..|...||:|.:.||.:|..||...
Mouse   166 KGKRKDFYRSVSLGLNRPLFSVYRRVVRMYDDRNHVGKYSPEEIEKLKELWQKHGNDWITIGAAM 230

  Fly   115 KDRLEQQVQQRWAKVLNPELIKGPWTRDED----DMVIKLVRNFGPKK------WTLIARYLNGR 169
             .|....|:.| .:::......|.||.:|:    |:|.:|......:|      |..:|:.:..|
Mouse   231 -GRSPSSVKDR-CRLMKDTCNTGKWTEEEEQLLGDVVHELTCTEVDEKVTHGVCWATVAQRVGTR 293

  Fly   170 IGKQCRERWHNHLNPNIKKTA---WTEKEDEIIYQAHLELG------NQWAKIAKRLPG-RTDNA 224
            ..||||.:|.|:|  |.|:|.   ||.|::..:.|..:||.      .:|.::||.... |:...
Mouse   294 SAKQCRAKWLNYL--NWKQTGGIEWTRKDEVTLIQRLVELDVSDESEIRWDELAKGWESVRSPQW 356

  Fly   225 IKNHW------------------NSTMRRKYDVERRSV----NASGSDLKSSRTHLI-------- 259
            ::|.|                  ...::::|:.:..|:    |.|||::..|...:|
Mouse   357 LRNKWWIIKRQITNHKDFAFPVLVRCLQQEYESQNASLRFWENKSGSEVPDSNPDIIFQQVPFGV 421

  Fly   260 TLIKSGGISKCMNNM 274
            |.|::...|.|.:.|
Mouse   422 TSIENNNASICTDPM 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myb	NP_511170.1	SANT	85..132	CDD:197842	14/59 (24%)
		Myb_DNA-bind_6	88..147	CDD:290632	18/62 (29%)
		SANT	136..184	CDD:197842	18/57 (32%)
		Myb_DNA-bind_6	139..197	CDD:290632	23/70 (33%)
		SANT	188..235	CDD:197842	13/74 (18%)
		Myb_DNA-binding	188..233	CDD:278669	13/72 (18%)
		Cmyb_C	388..530	CDD:286408
Dmtf1l	NP_808373.1	SANT	202..247	CDD:197842	13/46 (28%)
		Myb_DNA-bind_6	205..261	CDD:290632	17/57 (30%)
		SANT	251..307	CDD:197842	18/57 (32%)
		Myb_DNA-binding	251..306	CDD:278669	17/54 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2047
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930