Protein Alignment CG8578 and Lrrfip2

DIOPT Version :10

• Sequence 1: NP_573082.1
• Gene: CG8578 / 32540
• FlyBaseID: FBgn0030699
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: XP_011241302.1
• Gene: Lrrfip2 / 71268
• MGIID: 1918518
• Length: 748
• Species: Mus musculus
• Alignment Length: 746
• Identity: 196/746 - (26%)
• Similarity: 275/746 - (36%)
• Gaps: 365/746 - (48%)

  Fly     7 TGRRRNNM--RINAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKE----------- 58
            :||:|..:  |.:|||.||..|.:||||||||:|.||||||:||||||||||:|
Mouse     6 SGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQREPSHHHSFDRKW 70

  Fly    59 --------------------------------------------QEITA---------------- 63
                                                        ::||.
Mouse    71 GEIHKWLEDSERARYSHRSGHRRPYLGVEDTLSLRSLGSHRSSSKDITGTHWSRASTPKRRDMMY 135

  Fly    64 ----DR--------------------------------VFDMQNSTA-----------VGSETLS 81
                ||                                .||.:|.::           :.|.:|.
Mouse   136 DTIKDRPSRVSSLNHSYSHTHGTKKRSSSSYKDPLSGLYFDQRNYSSLRHSKPASTYYLRSSSLC 200

  Fly    82 AHPV------------------------RLAYGGLLN-------------VTRASASRRS----- 104
            :.|:                        .|..|||.|             .:|||:||.|
Mouse   201 SEPMGTPKSQSRASPTVTSGLLRSTSLASLYDGGLYNPYGSRTPSEYSYYSSRASSSRSSPVPID 265

  Fly   105 -------SED------------------------------------------SVEE--------- 111
                   |.|                                          |::|
Mouse   266 DDTASIVSSDRASRGRRESVVSMVSAADYFSRSNRRGSVVSEVDDAGISDLTSLDEKSDKQYAEN 330

  Fly   112 ------------------------------------------------------EGR---SFRDF 119
                                                                  |||   ..::.
Mouse   331 YTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIHDVEGRYMQGLKEL 395

  Fly   120 KHELKDVEERFRKAMITNAQLDNDRASQAYEVKLLKDKCEIMEESYAQLQREFKEKMRD------ 178
            |..|.:|||:::|||::||||||::.:..|:|..|||..|..||..|:..||.:||.::
Mouse   396 KESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKH 460

  Fly   179 -CNALKRNLDRANLELK--------LVQ------------------------------GQL---- 200
             |:.|:..:|    |||        |::                              |.|
Mouse   461 MCSVLQHKMD----ELKEGLRQRDELIEENQRLQQKVDTMTKEVFDLQETLLWKDKALGALEKQK 521

  Fly   201 -------NERDSL------------IAEQGLLIVAVENADGSDAKR-------ALVSVENAKVLA 239
                   ||||.|            .||:..|::..::....|...       ..||.|.|:||.
Mouse   522 EHIACLRNERDVLREELADLRQTVTTAEKHGLVIIPDSTPNGDVHHEPVVGAITAVSQEAAQVLE 586

  Fly   240 SV-QGSLDVRLKKFSDEKQRLLAEVQKLHEQLDE-----YKSDGISG-RRSLSQGSFGDENDYEA 297
            |. :|.|||||:|.:.||..||::::||..||:|     .::||:|| ...|..||  |....|.
Mouse   587 SAGEGPLDVRLRKLAGEKDELLSQIRKLKLQLEEERQKCSRNDGMSGDLAGLQNGS--DLQFIEM 649

  Fly   298 QRETNKIISDHKYKLQKAEQEIANLQSSLARSETQVIRYKSTAEAAEKAEAELKLERRKLQREHR 362
            ||:.|:.||::|:||.||||:||.|:.|::|.|.||:|||:.||.|||.|.|||.||||||||.|
Mouse   650 QRDANRQISEYKFKLSKAEQDIATLEQSISRLEGQVLRYKTAAENAEKIEDELKAERRKLQRELR 714

  Fly   363 ELLEKLEEAETSNNHLLKRLDKLKNAKSAIL 393
            ...:|:||.|.:|:||.|||:|:|..::|:|
Mouse   715 TAQDKIEEMEMTNSHLAKRLEKMKANRTALL 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8578	NP_573082.1	LRRFIP	47..321	CDD:462869	129/630 (20%)
Lrrfip2	XP_011241302.1	LRRFIP	319..673	CDD:462869	94/359 (26%)
		EnvC	653..>748	CDD:443969	53/93 (57%)