Protein Alignment CG8578 and flap-1

DIOPT Version :9

• Sequence 1: NP_001285302.1
• Gene: CG8578 / 32540
• FlyBaseID: FBgn0030699
• Length: 396
• Species: Drosophila melanogaster
• Sequence 2: NP_741208.1
• Gene: flap-1 / 175964
• WormBaseID: WBGene00018998
• Length: 373
• Species: Caenorhabditis elegans
• Alignment Length: 402
• Identity: 109/402 - (27%)
• Similarity: 204/402 - (50%)
• Gaps: 53/402 - (13%)

  Fly     1 MESISTTGRRRNNMRINAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEITADR 65
            |.|..::||||...|..||:.|||:|::|||||:..:|:.|.:||:.|.:.||::.:|
 Worm     1 MSSYPSSGRRRPITRSEAEERALDKISREAEARMKLKRETREQARQGRYQLLEKKVEE------- 58

  Fly    66 VFDMQNSTAVGSETLSAHPVRLAYGGLLNVTRASASRRSSEDSVEEEGRSFRDFKHELKDVEERF 130
                 ::.|...:|.|..          |....|:....:::.:.:          ::.::::|.
 Worm    59 -----DAEAYRHDTASTS----------NTNGVSSQSNQTQEQLHD----------KVIELQDRV 98

  Fly   131 RKAMITNAQLDNDRASQAYEVKLLKDKCEIMEESYAQLQREFKEKMRDCNALKRNLDRANLELKL 195
            ::.|...:||||::::..|||.||||:.|..:.|.....||.::...:..||||.:|..:...:.
 Worm    99 QQVMFLYSQLDNEKSTLLYEVDLLKDELEEKDASLNLSSRECRDLTSEVKALKRTIDALHASQQQ 163

  Fly   196 VQGQLNERDSLIAEQGLLIVAVENAD-GSDA---------------KRALVSVENAKVLASVQGS 244
            ::.::::||.||.|.||.:|..:..| ||::               ||..:.:.:..|..:  .|
 Worm   164 LKQEISQRDQLIQENGLCLVEEDPDDEGSESTNNASGEIRSGPYLFKRETIRLVDRVVPGA--AS 226

  Fly   245 LDVRLKKFSDEKQRLLAEVQKLHEQLDEYKSDGISGRRSLSQGSFGDENDYEAQRETNKIISDHK 309
            ||.:::|..|..:::..:.::|.:.:  |........|. |.....::...:..::..|.:::.|
 Worm   227 LDDKIQKLVDTNKKMRKDYEELEQTI--YTQRHARNARD-SANVIPNQGVDDVNKDAAKQLAEMK 288

  Fly   310 YKLQKAEQEIANLQSSLARSETQVIRYKSTAEAAEKAEAELKLERRKLQREHRELLEKLEEAETS 374
            .|:|..|:|..|.|.::.|.|.|:.||||.|:.|||...|||.:.|:.::|.|:....|:|.:.:
 Worm   289 LKMQDLERENTNQQGNVIRMEGQMKRYKSNADVAEKELDELKTQMRQTKKELRDKENALDEQKET 353

  Fly   375 NNHLLKRLDKLK 386
            |.||..||:|::
 Worm   354 NKHLQSRLEKMR 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8578	NP_001285302.1	DUF2051	47..321	CDD:286781	60/289 (21%)
flap-1	NP_741208.1	DUF2051	30..300	CDD:286781	68/306 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163726
Domainoid	1	1.000	70	1.000	Domainoid score	I6265
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22476
Inparanoid	1	1.050	148	1.000	Inparanoid score	I2998
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45893
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002905
OrthoInspector	1	1.000	-	-		oto20785
orthoMCL	1	0.900	-	-		OOG6_108791
Panther	1	1.100	-	-	LDO	PTHR19212
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4096
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.930