Protein Alignment ArgRS and MSR1

DIOPT Version :9

• Sequence 1: NP_573081.1
• Gene: ArgRS / 32539
• FlyBaseID: FBgn0027093
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_011959.1
• Gene: MSR1 / 856491
• SGDID: S000001133
• Length: 643
• Species: Saccharomyces cerevisiae
• Alignment Length: 576
• Identity: 160/576 - (27%)
• Similarity: 252/576 - (43%)
• Gaps: 112/576 - (19%)

  Fly   143 ATELKGH------CPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVKPPEVI------- 194
            |.||..|      |...|           |:..||.:.|       |:::.|  |.::
Yeast   127 AIELSTHGCIGKVCAKGP-----------FLQFFLDQRY-------LIQSTV--PNILLQKGKYG 171

  Fly   195 ------KKRVLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLI 253
                  :|:|:|:||||||||..|.|||||||||..|..|.|.:...|.|:|:|||||.|||:|.
Yeast   172 QKKSRHQKKVVVEFSSPNIAKPFHAGHLRSTIIGGFLSNLYEAMGWSVTRMNYLGDWGRQFGLLA 236

  Fly   254 AHLEDRFPNYLNE----SPPISDLQLFYKESKKRFDEDE-------EFKKRAYSRVVSLQKGVPN 307
            .    .|..|.:|    ..||..|...|.:......::|       .....|.|...:|:.|..|
Yeast   237 V----GFKRYGDEKTLQKQPIQHLFDVYVKINMDLAKEEINGNSKCGISGEARSFFKNLENGDEN 297

  Fly   308 SIKAWELICNVSRKEFQTIYERLDISVK-ERGES-FYQSRMLSVVEYLRGKGLLEVDEGREIM-- 368
            :||.|....::|...:...|.||:|:.. ..||| ..:..|...::..|...|::..:|..::
Yeast   298 AIKIWNRFRSLSIHHYIQTYSRLNINFDIFSGESQVSKESMNEALDIFRKNNLVKEIDGALVIDL 362

  Fly   369 --WPDDTKTGIPLTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHFNTIFKAAER 431
              |   :|....:.:.||||...|.|.|:.|...|.:....|.::||:.|.|..:.:..|
Yeast   363 TQW---SKRLGRVVVQKSDGTTLYLTRDVGAAIERKKNLHFDKMVYVISSQQDLYMSQFF----- 419

  Fly   432 SAILNPLSHR----VDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLDEGMKRSLQQLESRGR--DK 490
             .||..::..    :.|:.||:|.|     ..||.|:.|.|..:|||...::||.:|:...  .:
Yeast   420 -MILKKMNFEWAKDLQHINFGMVQG-----MSTRKGNVVFLDTILDEARDKALQIMENNKMKISQ 478

  Fly   491 VLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICSIARNSG 555
            |..||.:.|.   :....|...|:...||::|.|::::||...|:|..||.||::|:.|:.|.|.
Yeast   479 VDNPQRVADL---IGVSAIIIQDMKSKRINNYEFNWNRMLSFEGDTGPYLQYTHSRLRSLERTSS 540

  Fly   556 E---------DFTNL--PEILKKTNIVLDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFE 609
            :         ||:||  |:::             :|.:.|.:..|:|.:..:......:..:.|:
Yeast   541 DFTTDMLIHADFSNLNEPQLV-------------ELVRLLAQYPDVLRRAFETQEPATIVTYLFK 592

  Fly   610 VCTVFTEFYDSCYCIEKNKQGDIIGVNHSRILLCEATAAVLRQCFYILGLKPVSKM 665
            ||...:..|...:.  ..|..||.   ..|:.:..|:..||.....:|||.||.:|
Yeast   593 VCHQVSSCYKKIWV--SGKPADIA---IPRLAVYSASRQVLHNAMSLLGLVPVDRM 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS	NP_573081.1	Arg_tRNA_synt_N	81..171	CDD:214975	7/33 (21%)
		PLN02286	83..665	CDD:215160	159/574 (28%)
		ArgRS_core	197..463	CDD:185675	89/286 (31%)
		DALR_1	540..665	CDD:214846	32/135 (24%)
MSR1	NP_011959.1	argS	69..643	CDD:273085	159/574 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343010
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60659
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100350
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1455
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.680