Protein Alignment ArgRS and YDR341C

DIOPT Version :9

• Sequence 1: NP_573081.1
• Gene: ArgRS / 32539
• FlyBaseID: FBgn0027093
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_010628.3
• Gene: YDR341C / 851942
• SGDID: S000002749
• Length: 607
• Species: Saccharomyces cerevisiae
• Alignment Length: 680
• Identity: 194/680 - (28%)
• Similarity: 293/680 - (43%)
• Gaps: 142/680 - (20%)

  Fly    50 NRLFILKK-SIAEESTAAGGDVSKPKESS---SITEHLESVFRQAIASAFPEFRDTPVIIAPVNS 110
            |.:..||| ||||.:.|        |:|.   :|.:.:.:...|.::.           |:.|:|
Yeast     6 NMISQLKKLSIAEPAVA--------KDSHPDVNIVDLMRNYISQELSK-----------ISGVDS 51

  Fly   111 TSAKFGDYQCNNAMGLS------KKLKEKGINKAPRDIATELKGHCPASPIIEKLEIAGAGFVNV 169
             |..|...:..|.|...      .:|:.||.|  |:|:|.:.....|....:||:| |...|:..
Yeast    52 -SLIFPALEWTNTMERGDLLIPIPRLRIKGAN--PKDLAVQWAEKFPCGDFLEKVE-ANGPFIQF 112

  Fly   170 FLSKDY-ASLALSNLLR-----NGVKPPEVIKKRVLVDFSSPNIAKQMHVGHLRSTIIGESLCRL 228
            |.:..: |.|.:.::|.     ...|..|  .|:|:::||||||||..|.|||||||||..|..|
Yeast   113 FFNPQFLAKLVIPDILTRKEDYGSCKLVE--NKKVIIEFSSPNIAKPFHAGHLRSTIIGGFLANL 175

  Fly   229 LEFLQHDVIRINHLGDWGTQFGMLIAHLEDRFPNYLNE----SPPISDLQLFYKESKKRFDEDEE 289
            .|.|..:|||:|:|||||.|||:|..    .|..|.||    ..||..|...|....|..:|:.:
Yeast   176 YEKLGWEVIRMNYLGDWGKQFGLLAV----GFERYGNEEALVKDPIHHLFDVYVRINKDIEEEGD 236

  Fly   290 F---------KKRAYSRVVSLQKGVPNSIKAWELICNVSRKEFQTIYERLDISVK-ERGES-FYQ 343
            .         |.|.|.:  .::.|...::|.|:.....|.:::...|.||:|... ..||| ..:
Yeast   237 SIPLEQSTNGKAREYFK--RMEDGDEEALKIWKRFREFSIEKYIDTYARLNIKYDVYSGESQVSK 299

  Fly   344 SRMLSVVEYLRGKGLLEVDEGREIMWPDDTKTGIPL---TIVKSDGGFTYDTSDMAAIRHRLEEE 405
            ..||..::..:.|||...|:|..::  |.||....|   .:.||||...|.|.|:.|...|.|:.
Yeast   300 ESMLKAIDLFKEKGLTHEDKGAVLI--DLTKFNKKLGKAIVQKSDGTTLYLTRDVGAAMDRYEKY 362

  Fly   406 LCDWIIYVVDSGQSTHFNTIFKAAERSAILNPLSHR----VDHVQFGVVLGEDGKKFKTRSGDTV 466
            ..|.:|||:.|.|..|      ||:...||..:...    :.||.||:|.|     ..||.|..|
Yeast   363 HFDKMIYVIASQQDLH------AAQFFEILKQMGFEWAKDLQHVNFGMVQG-----MSTRKGTVV 416

  Fly   467 KLSDLLDEGMKRSLQQLESRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLE 531
            .|.::|:| .|..:.::..:..:|....:..::..:.:....:...|:...||::|.|.:::||.
Yeast   417 FLDNILEE-TKEKMHEVMKKNENKYAQIEHPEEVADLVGISAVMIQDMQGKRINNYEFKWERMLS 480

  Fly   532 DRGNTAVYLLYTYTRICSIARNS---------GEDFTNLPEILKKTNIVLDHEKEWKLAKTLLKL 587
            ..|:|..||.|.::|:.|:.||:         ..||:.|.|               ..||.|::|
Yeast   481 FEGDTGPYLQYAHSRLRSVERNASGITQEKWINADFSLLKE---------------PAAKLLIRL 530

  Fly   588 ----HDILIKCSKELFLHFLCEFCFEVCTVFTEFY------DSCYCIEKNKQGDIIGV------- 635
                .|:|....|          ..|..||.|..:      .|||        |::.|
Yeast   531 LGQYPDVLRNAIK----------THEPTTVVTYLFKLTHQVSSCY--------DVLWVAGQTEEL 577

  Fly   636 NHSRILLCEATAAVLRQCFYILGLKPVSKM 665
            ..:|:.|..|...||.....:|||.||.:|
Yeast   578 ATARLALYGAARQVLYNGMRLLGLTPVERM 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS	NP_573081.1	Arg_tRNA_synt_N	81..171	CDD:214975	21/95 (22%)
		PLN02286	83..665	CDD:215160	181/641 (28%)
		ArgRS_core	197..463	CDD:185675	100/287 (35%)
		DALR_1	540..665	CDD:214846	36/150 (24%)
YDR341C	NP_010628.3	argS	31..607	CDD:273085	182/645 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343008
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60659
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100350
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1455
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.680