DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ArgRS and emb1027

DIOPT Version :9

Sequence 1:	NP_573081.1	Gene:	ArgRS / 32539	FlyBaseID:	FBgn0027093	Length:	665	Species:	Drosophila melanogaster
Sequence 2:	NP_001329503.1	Gene:	emb1027 / 828736	AraportID:	AT4G26300	Length:	653	Species:	Arabidopsis thaliana

Alignment Length:	600	Identity:	280/600 - (46%)
Similarity:	387/600 - (64%)	Gaps:	27/600 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 SSSITEHLESVFRQAIASAFPEFRDTPVIIAPVNSTSA--KFGDYQCNNAMGLSKKLKEKGIN-K 137
            :.::...|..:|..::....|   |.| .:.|:.:.||  |||||||||||||...:|.||.. |
plant    71 TGNLKRQLAKLFDVSLKLTVP---DEP-SVEPLVAASALGKFGDYQCNNAMGLWSIIKGKGTQFK 131

  Fly   138 APRDIATELKGHCPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVK--PPEVIKKRVLV 200
            .|..:...|....|.|.::|...:||.||:||.||..:.:.::.|:|.:||.  .|.:..||.:|
plant   132 GPPAVGQALVKSLPTSEMVESCSVAGPGFINVVLSAKWMAKSIENMLIDGVDTWAPTLSVKRAVV 196

  Fly   201 DFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLIAHLEDRFP--NY 263
            |||||||||:||||||||||||::|.|:||:...:|:|.||:|||||||||||.:|.::||  :.
plant   197 DFSSPNIAKEMHVGHLRSTIIGDTLARMLEYSHVEVLRRNHVGDWGTQFGMLIEYLFEKFPDTDS 261

  Fly   264 LNESPPISDLQLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVPNSIKAWELICNVSRKEFQTIYE 328
            :.|: .|.|||:|||.||.:||.||.||::|...||.||.|.|...|||..||::||.||..:|:
plant   262 VTET-AIGDLQVFYKASKHKFDLDEAFKEKAQQAVVRLQGGDPVYRKAWAKICDISRTEFAKVYQ 325

  Fly   329 RLDISVKERGESFYQSRMLSVVEYLRGKGLLEVDEGREIMWPDDTKTGIPLTIVKSDGGFTYDTS 393
            ||.:.::|:|||||...:..|:|.|..|||:|..||..:::.:.  ..|||.:|||||||.|.::
plant   326 RLRVELEEKGESFYNPHIAKVIEELNSKGLVEESEGARVIFLEG--FDIPLMVVKSDGGFNYAST 388

  Fly   394 DMAAIRHRLEEELCDWIIYVVDSGQSTHFNTIFKAAERSAIL--NPLSH-RVDHVQFGVVLGEDG 455
            |:.|:.:||.||..:|||||.|.||..|||..||||.::..|  |..:: ||:||.||:||||||
plant   389 DLTALWYRLNEEKAEWIIYVTDVGQQQHFNMFFKAARKAGWLPDNDKTYPRVNHVGFGLVLGEDG 453

  Fly   456 KKFKTRSGDTVKLSDLLDEGMKRSLQQLESRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRIS 520
            |:|:||:.|.|:|.|||||...||...|..||:||..||:||....|::.||.:||:||.:||::
plant   454 KRFRTRATDVVRLVDLLDEAKTRSKLALIERGKDKEWTPEELDQTAEAVGYGAVKYADLKNNRLT 518

  Fly   521 DYIFSFDKMLEDRGNTAVYLLYTYTRICSIARNSGEDFTNLPEILKKTNIVLDHEKEWKLAKTLL 585
            :|.||||:||.|:|||||||||.:.|||||.|.||:|   :.|:.|...:.|||..|..|...||
plant   519 NYTFSFDQMLNDKGNTAVYLLYAHARICSIIRKSGKD---IDELKKTGKLALDHADERALGLHLL 580

  Fly   586 KLHDILIKCSKELFLHFLCEFCFEVCTVFTEFYDSCYCIEKNKQGDIIGVNHSRILLCEATAAVL 650
            :..:.:.:....|....|||:.:.:...||.||.:|   :.|...:    ..||:|||||||.|:
plant   581 RFAETVEEACTNLLPSVLCEYLYNLSEHFTRFYSNC---QVNGSPE----ETSRLLLCEATAIVM 638

  Fly   651 RQCFYILGLKPVSKM 665
            |:||::||:.||.|:
plant   639 RKCFHLLGITPVYKI 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS	NP_573081.1	Arg_tRNA_synt_N	81..171	CDD:214975	36/92 (39%)
		PLN02286	83..665	CDD:215160	279/591 (47%)
		ArgRS_core	197..463	CDD:185675	145/270 (54%)
		DALR_1	540..665	CDD:214846	48/124 (39%)
emb1027	NP_001329503.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	349	1.000	Domainoid score	I224
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68281
Inparanoid	1	1.050	508	1.000	Inparanoid score	I306
OMA	1	1.010	-	-		QHG60659
OrthoDB	1	1.010	-	-		D463402at2759
OrthoFinder	1	1.000	-	-		FOG0004174
OrthoInspector	1	1.000	-	-		otm3131
orthoMCL	1	0.900	-	-		OOG6_100350
Panther	1	1.100	-	-	LDO	PTHR11956
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2924
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840