Protein Alignment ArgRS and Rars2

DIOPT Version :9

• Sequence 1: NP_573081.1
• Gene: ArgRS / 32539
• FlyBaseID: FBgn0027093
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001100113.1
• Gene: Rars2 / 297969
• RGDID: 1305419
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 183/618 - (29%)
• Similarity: 297/618 - (48%)
• Gaps: 83/618 - (13%)

  Fly    87 FRQAIASAF-------PEFRDTPVIIAPVNSTSAKFGDYQCNNAMGLSKKLKEKGINKAPRDIAT 144
            ||::||...       ||.....:...|| |...:..|:|.:     ...|.|...:|:..|...
  Rat     5 FRRSIACQLSRVLALPPESLIKSISAVPV-SKKEEVADFQLS-----VDSLLENNSHKSQLDTQD 63

  Fly   145 ELKGHCPASPIIEKLEI--------AGAGFVNVFLSKDYASLA-LSNLLRNGVKP-------PEV 193
            :      |..:.|||:.        ||...:|..:::...:.| |..:..:|.|.       .::
  Rat    64 Q------AQRLAEKLKCDTVVTAISAGPRTLNFKINRALLTKAVLQQVTEDGSKYGLKSELFSDL 122

  Fly   194 IKKRVLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGML-----I 253
            .:||::|:||||||||:.|||||||||||..:..|.|.|.|.|.|||::||||.|||:|     :
  Rat   123 PQKRIVVEFSSPNIAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYIGDWGMQFGLLGTGFQL 187

  Fly   254 AHLEDRFPNYLNESPPISDLQLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVPNSIKAWELICNV 318
            ...|::.     ::.|:..|...|.:..|...:|:...|.|:.....|:.|...::..|:...::
  Rat   188 FGYEEKL-----QANPLQHLFDVYVQVNKEATDDKNVTKLAHEFFHRLELGDTQALALWQRFRDL 247

  Fly   319 SRKEFQTIYERLDISVKE-RGESFYQSRMLSVVEYLRGKGLLE-VDEGREIMWPDDTKTG---IP 378
            |.:|:..||:||.|...| .|||||:.:...|::.|..||||: ..:|..::  |.::||   ..
  Rat   248 SIEEYTQIYKRLGIYFDEYSGESFYREKSQDVLKLLDSKGLLQKTAKGNVVV--DVSETGDLSSV 310

  Fly   379 LTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHFNTIFKAAERSAILNPLSH--- 440
            .|:::|||...|.|.|:||..||.::...|.:|||.|.||..||..:|:      :|..:.|
  Rat   311 CTVMRSDGTSLYATRDLAAAIHRKDKYNFDTMIYVADKGQKRHFQQVFQ------MLKIMGHEWA 369

  Fly   441 -RVDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLDEGMKRSLQQLES-RGRDKVLTPQELKDAQES 503
             |..||.||:|.|     .|||.|:...|.|:|:|...|.||.:.| :...|:..|:|   ..|.
  Rat   370 ERCQHVPFGIVKG-----MKTRRGEVTFLEDVLNEVQSRMLQNMASIKTTKKMENPRE---TAEK 426

  Fly   504 LAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICSIARNSGEDFTNLPEILKKT 568
            :....:...|.....:|||.||:|::.:.||:|.|:|.||:.|:||:....|..:.|      ..
  Rat   427 VGLAALIIQDFRGLLLSDYQFSWDRVFQSRGDTGVFLQYTHARLCSLEETFGCGYLN------DF 485

  Fly   569 NIV-LDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFEVCTVFTEFYDSCYCIEKNKQGDI 632
            |:. |...:...:.:.||:..::|...|::|....:..:...:..:....:.:...  |:...::
  Rat   486 NVACLQEPQSVSILQHLLRFDEVLYTASQDLQPKHIVSYLLTLSHLAAVAHKTLQV--KDSPPEV 548

  Fly   633 IGVNHSRILLCEATAAVLRQCFYILGLKPVSKM 665
            .|   :|:.|.:|..:||.....:||:.||.||
  Rat   549 AG---ARLHLFKAVRSVLANGMKLLGITPVCKM 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS	NP_573081.1	Arg_tRNA_synt_N	81..171	CDD:214975	22/98 (22%)
		PLN02286	83..665	CDD:215160	181/616 (29%)
		ArgRS_core	197..463	CDD:185675	104/279 (37%)
		DALR_1	540..665	CDD:214846	26/125 (21%)
Rars2	NP_001100113.1	ArgS	30..578	CDD:223097	175/591 (30%)
		ArgRS_core	126..388	CDD:185675	104/279 (37%)
		Anticodon_Ia_like	425..578	CDD:299868	38/163 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60659
OrthoDB	1	1.010	-	-		D463402at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100350
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.730