Protein Alignment ArgRS and mrs1

DIOPT Version :9

• Sequence 1: NP_573081.1
• Gene: ArgRS / 32539
• FlyBaseID: FBgn0027093
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_596077.1
• Gene: mrs1 / 2540548
• PomBaseID: SPBC25B2.09c
• Length: 618
• Species: Schizosaccharomyces pombe
• Alignment Length: 636
• Identity: 169/636 - (26%)
• Similarity: 278/636 - (43%)
• Gaps: 108/636 - (16%)

  Fly    86 VFRQAIASAFPEFRDTPV-IIAPVNSTSAKFGDYQCN------NAMGLSKKLKEKGINKAPRDIA 143
            |:|..|:|...:.....| :|.|...||........|      ...|..::|.:|.....|:|:
pombe    35 VYRSYISSELSKINGVDVSLIYPALETSISKDSADLNLPVPRLRVKGKPQELAQKWAEAFPKDL- 98

  Fly   144 TELKGHCPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVKPPEVIKKR----------- 197
                           :|:...|   :||..::...:|:.|:.     |.:.::|
pombe    99 ---------------VEVTANG---IFLRFNFNGPSLTKLIL-----PIIWEQRENYGRNESGSG 140

  Fly   198 --VLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLIAHL---- 256
              .:::||||||||..|.|||||||||..|..|.|.....|.|:|:|||||.|||:|....
pombe   141 KVAVIEFSSPNIAKPFHAGHLRSTIIGSFLANLHESQGWKVHRVNYLGDWGKQFGLLAIGYKKYG 205

  Fly   257 -EDRFPNYLNESPPISDL-QLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVP------------- 306
             ||:.     :|.||..| .::.|.:....:|||:.:|   .:..:..||:|
pombe   206 DEDQL-----KSNPIRHLYDVYVKVNADATEEDEKIQK---DKAEAESKGLPYTPPLSLHDKARE 262

  Fly   307 ----------NSIKAWELICNVSRKEFQTIYERLDISVKE-RGESFYQSRMLS-VVEYLRGKGLL 359
                      .|:|.|....::|..:.:..|:||:|...| .|||.....::: :|:.||...|:
pombe   263 FFKRMEDGDEESLKVWARFRDLSITKLKDTYDRLNIHYDEYDGESQVSLELMNKMVDELRSLNLI 327

  Fly   360 EVDEGREI--MWPDDTKTGIPLTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHF 422
            |.|.|..:  :...|.|.|..: :.|.||...|.|.|:.....|.|:...|..||||.|.|..:|
pombe   328 EEDGGALLIDLSKHDKKLGKAI-VQKRDGTTLYLTRDIGTAYKRYEKYKFDKSIYVVSSQQDMYF 391

  Fly   423 NTIFKAAERSAILNPLSHRVDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLD---EGMKRSLQQLE 484
            :.:||..|....  ..:.:..|:.:|:|.|     ..||.|..|.|.|:::   |.|.:.:|:.|
pombe   392 SQLFKIFELMGF--DWAKKCVHINYGLVQG-----MSTRKGKAVFLDDIMEVAKEEMHKVMQKNE 449

  Fly   485 SRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICS 549
            .: ..:|..|:|:.|.....|   |:..|....||::|.|.:.:|....|:|..||.|.::|:.|
pombe   450 EK-YAQVENPEEVADIVGKTA---IRIQDSTGKRINNYAFDWSRMTSFEGDTGPYLQYAHSRLSS 510

  Fly   550 IARNSGEDFTNLPEILKKTNIVLDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFEVCTVF 614
            :.||  .::|: .||:.....:|.....:.|.:.|.:..|:|....:......:..:.|::....
pombe   511 VRRN--VNYTD-EEIMGANLELLTEPDAYDLVRLLGQYPDVLKNAFRFQETSTVVTYLFKLTHAV 572

  Fly   615 TEFYDSCYCIEKNKQGDIIGVNHSRILLCEATAAVLRQCFYILGLKPVSKM 665
            ::.||..:.  :.::.||   ..:|:.|..|...||.....:|||.|:.:|
pombe   573 SKLYDILWV--RGRERDI---QLARLALFGAAKQVLNNGMTLLGLTPLERM 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS	NP_573081.1	Arg_tRNA_synt_N	81..171	CDD:214975	17/91 (19%)
		PLN02286	83..665	CDD:215160	168/634 (26%)
		ArgRS_core	197..463	CDD:185675	95/311 (31%)
		DALR_1	540..665	CDD:214846	28/124 (23%)
mrs1	NP_596077.1	ArgS	30..618	CDD:223097	168/634 (26%)
		Arg_tRNA_synt_N	34..112	CDD:214975	19/95 (20%)
		ArgRS_core	144..425	CDD:185675	94/296 (32%)
		Anticodon_Ia_Arg	463..618	CDD:153410	40/165 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0018
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60659
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100350
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1455
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750