Protein Alignment CG8565 and mapk10

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_001305248.1
• Gene: mapk10 / 569698
• ZFINID: ZDB-GENE-051120-117
• Length: 486
• Species: Danio rerio
• Alignment Length: 683
• Identity: 123/683 - (18%)
• Similarity: 206/683 - (30%)
• Gaps: 329/683 - (48%)

  Fly   141 KYSELSYGSESSMPFEMKQQSNDNQNNNDNAEGSGFDRQESANEYVIGGYHPVAIGD---VFVNR 202
            |..::||.::.   :.|.:...|||                        ::.|.:||   ..:.|
Zfish    26 KQVDVSYIAQH---YNMSKSKVDNQ------------------------FYSVEVGDSTFTVLKR 63

  Fly   203 YHVFKKLGWGHFSTVWLCYDTQMDRYCAV-KVSK--SAQVYKETGIDEIMLFSQMSLHDQHKYRS 264
            |...|.:|.|....|...||..:||..|: |:|:  ..|.:.:....|::|...::    ||
Zfish    64 YQNLKPIGSGAQGIVCAGYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVN----HK--- 121

  Fly   265 HVVGFYDFF--EITGPHGRHICLVLEVLGDNLLKVI------ERCFYKGMPISNIKQIAQQVLTG 321
            :::...:.|  :.:....:.:.||:|::..||.:||      ||..|          :..|:|.|
Zfish   122 NIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSY----------LLYQMLCG 176

  Fly   322 LKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAKRRMQAK 386
            :|.|| ..||||.||||.|:::.|
Zfish   177 IKHLH-SAGIIHRDLKPSNIVVKS----------------------------------------- 199

  Fly   387 SKKVISFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDGFMMMSDADCRT 451
                                                                         ||
Zfish   200 -------------------------------------------------------------DC-- 201

  Fly   452 VQNSKLPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKNLDEKELSTQDKRRRFTQASGRGQTKK 516
                                 .||        :||.
Zfish   202 ---------------------TLK--------ILDF----------------------------- 208

  Fly   517 NARSRLRLASNAAYTTGTGWRSNRKINLNDIYPIDPANNECDVRVKIADLGNACYFHHHFTDDIQ 581
                      ..|.|.||.:.                                      .|..:.
Zfish   209 ----------GLARTAGTSFM--------------------------------------MTPYVV 225

  Fly   582 TKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGR-I 645
            |:.|||.|||||.||.|..|||||.|::.|:.....||.     |:..:|:.:  |::|..|. .
Zfish   226 TRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFP-----GRDYIDQWN--KVIEQLGTPS 283

  Fly   646 PWYLIRKGKHSRNFINSAGKLCNI-------ETLKPLKLANILIRWYGWRTRQSTEFVNFLMPML 703
            |.::.:.....||::.:..|...:       :.|.|....:..::        :::..:.|..||
Zfish   284 PEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDCLFPADSEHNKLK--------ASQARDLLSKML 340

  Fly   704 QTNPLSRISASKALESHYLCNIALPGIDIDSYYYYSVREIKDCTHTKSERNS----------DED 758
            ..:|..|||..:||:..|: |:           :|...|:      ::.||.          |:
Zfish   341 IIDPAKRISVDEALQHPYI-NV-----------WYDPAEV------EAARNQQISMPPPQIYDK- 386

  Fly   759 SSSCSSIDSSEFSSD---EVCYEDDVNEEDIKK 788
                 .:|..|.|.|   |:.|::.:|.|:..|
Zfish   387 -----QLDEREHSIDEWKELIYKEVMNFEERTK 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	100/551 (18%)
mapk10	NP_001305248.1	STKc_JNK	63..406	CDD:270840	110/609 (18%)