Protein Alignment CG8565 and mapk6

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_001039017.1
• Gene: mapk6 / 565830
• ZFINID: ZDB-GENE-050420-7
• Length: 729
• Species: Danio rerio
• Alignment Length: 633
• Identity: 105/633 - (16%)
• Similarity: 183/633 - (28%)
• Gaps: 303/633 - (47%)

  Fly   202 RYHVFKKLGWGHFSTVWLCYDTQMDRYCAVK--VSKSAQVYKETGIDEIMLFSQMSLHDQHKYRS 264
            ||...|.||:|....|:...||..|:..|||  |....|..|. .:.||.:..::. ||
Zfish    19 RYMDLKPLGYGGNGLVFSAVDTDCDKRVAVKKIVLTDPQSVKH-ALREIKIIRRLD-HD------ 75

  Fly   265 HVVGFYDFFEITGPHGRH-------------ICLVLEVLGDNLLKVIERCFYKGMPISNIKQIAQ 316
               .....||..||.||.             :.:|.|.:..:|.||:|:..   :...:.:....
Zfish    76 ---NIVKVFETLGPSGRRLTEDVSSLTEVNSVYIVQEYMETDLCKVLEQGL---LSEDHARLFMY 134

  Fly   317 QVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAKR 381
            |:|.|||::| ...::|.||||.|:.       |.||
Zfish   135 QLLRGLKYIH-SANVLHRDLKPANLF-------VNTE---------------------------- 163

  Fly   382 RMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDGFMMMSD 446
                                                                             
Zfish   164 ----------------------------------------------------------------- 163

  Fly   447 ADCRTVQNSKLPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKNLDEKELSTQDKRRRFTQASGR 511
                                                                             
Zfish   164 ----------------------------------------------------------------- 163

  Fly   512 GQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIYPIDPANNECDVRVKIADLGNA-----CY 571
                                                          |:.:||.|.|.|     .|
Zfish   164 ----------------------------------------------DLVLKIGDFGLARIMDPHY 182

  Fly   572 FHH-HFTDDIQTKEYRALEVILGA-GYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVH 634
            .|. |.::.:.||.||:..::|.. .|.:..|:|:..|:..|:.||..||     .|.:.|:::.
Zfish   183 SHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLF-----AGAHELEQMQ 242

  Fly   635 IAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPL-----------KLANILIRWYGWR 688
            :  |:|:   ||            .::...:| .::::.|:           .||.:|
Zfish   243 L--ILES---IP------------VVHEEDRL-ELQSVIPVFIKNDMSEPHTPLAKLL------- 282

  Fly   689 TRQSTEFVNFLMPMLQTNPLSRISASKALESHYLCNIALPGIDIDSYYYYSVRE------IKDCT 747
            ...|.|.::||..:|..||:.|::|.:||...|:.:.:.|..:..|.:.:.:.:      :.|.:
Zfish   283 PGVSPEALDFLEKILTFNPMDRLTAEEALAHPYMSDYSFPLDEPVSLHPFHIEDEVDDILLMDES 347

  Fly   748 HT--------KSERNSDEDSSSCSSIDSSEFSSDEVCYEDDVNEEDIK 787
            |:        ...:.||:|....|:.:..:...|.....|..:||:::
Zfish   348 HSHVYNWDRYHESQFSDQDWHLHSTHELEDVQRDPRAMSDVTDEEEVQ 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	92/552 (17%)
mapk6	NP_001039017.1	STKc_MAPK4_6	14..355	CDD:143359	97/591 (16%)