Protein Alignment CG8565 and nlk2

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_001106957.3
• Gene: nlk2 / 563460
• ZFINID: ZDB-GENE-080320-1
• Length: 533
• Species: Danio rerio
• Alignment Length: 618
• Identity: 110/618 - (17%)
• Similarity: 172/618 - (27%)
• Gaps: 304/618 - (49%)

  Fly   207 KKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSL-----HDQHKYRSHV 266
            :.:|:|.|..||...|.:..:..|:|  |...|::.. :....:|.::.:     ||      :|
Zfish   148 RPIGYGAFGVVWSVTDPRDGKRVALK--KMPNVFQNL-VSCKRVFRELKMLCFFKHD------NV 203

  Fly   267 VGFYDFFEITGPH---GRHICLVLEVLGDNLLKVIERCFYKGMPIS--NIKQIAQQVLTGLKFLH 326
            :...|..:  .||   ...|.:|.|::..:|.|:|    ....|:|  ::|....|:|.|||:||
Zfish   204 LSALDILQ--PPHIDYFEEIYVVTELMQSDLHKII----VSPQPLSSDHVKVFLYQILRGLKYLH 262

  Fly   327 EECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAKRRMQAKSKKVI 391
             ..||:|.|:||.|:|:.||.|             ||.
Zfish   263 -SAGILHRDIKPGNLLVNSNCV-------------LKI--------------------------- 286

  Fly   392 SFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDGFMMMSDADCRTVQNSK 456
                                                                             
Zfish   287 ----------------------------------------------------------------- 286

  Fly   457 LPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKNLDEKELSTQDKRRRFTQASGRGQTKKNARSR 521
                      ||              :.|..::.|||.
Zfish   287 ----------CD--------------FGLARVEELDES--------------------------- 300

  Fly   522 LRLASNAAYTTGTGWRSNRKINLNDIYPIDPANNECDVRVKIADLGNACYFHHHFTDDIQTKEYR 586
                                                                .|.|.::.|:.||
Zfish   301 ----------------------------------------------------RHMTQEVVTQYYR 313

  Fly   587 ALEVILGA-GYCETADIWSVACLLWELATGTYLFDTHSK----------RGKYNLDEVHIAKIVE 640
            |.|:::|: .|....|||||.|:..||.....||...|.          .|..:|:.:..|
Zfish   314 APEILMGSRHYSNAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTA---- 374

  Fly   641 TCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQT 705
             |.....:::| |.|.:            .:|..|         |...::.:.|.|:.|..||..
Zfish   375 -CEGARAHILR-GPHKQ------------PSLPVL---------YTLSSQATHEAVHLLCRMLVF 416

  Fly   706 NPLSRISASKALESHYL-----------CN-----------------IALPGIDIDSY--YYYSV 740
            :|..||||..||...||           |.                 :..|..| |.:  ...||
Zfish   417 DPSKRISAKDALAHPYLDEGRLRYHTCMCKCCYTTSSGRVYTSDFEPVTNPKFD-DGFEKNLTSV 480

  Fly   741 REIKDCTHT-KSERNSDEDSSSCSSIDSSEFSS 772
            |::|:..|. ..|:........|.:..|:.|.|
Zfish   481 RQVKEIIHQFILEQQKGNRVPLCINPQSAAFKS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	94/535 (18%)
nlk2	NP_001106957.3	None