Protein Alignment CG8565 and Srpk1

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_001020897.1
• Gene: Srpk1 / 361811
• RGDID: 1308272
• Length: 655
• Species: Rattus norvegicus
• Alignment Length: 691
• Identity: 238/691 - (34%)
• Similarity: 343/691 - (49%)
• Gaps: 130/691 - (18%)

  Fly   113 KKRCKQKRRMPSSLSDDGIAGRKPAKINKYSELSYGSESSMPFEMKQQSNDNQNNNDNAEGSGFD 177
            |||.|.|:..         |.|||...::.|  :..|||.:|           ...:...||..|
  Rat    12 KKRTKAKKDK---------AQRKPETQHRGS--APHSESDIP-----------EQEEEILGSDDD 54

  Fly   178 RQESANEYVIGGYHPVAIGDVFVNRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKE 242
            .||..|:|..||||.|.|||:|..||||.:||||||||||||.:|.|..::.|:||.|||:.|.|
  Rat    55 EQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTE 119

  Fly   243 TGIDEIMLFSQMSLHDQHKYRSH-VVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCFYKGM 306
            |.:|||.|...:...|.:..... ||...|.|:|:|.:|.|||:|.||||.:|||.|.:..|:|:
  Rat   120 TALDEIRLLKSVRNSDPNDPNGEMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGL 184

  Fly   307 PISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLS- 370
            |:..:|:|.||||.||.:||.:|.|||||:||||:||:.||..:|   :.|.|    |.|.:.|
  Rat   185 PLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIR---RLAAE----ATEWQRSG 242

  Fly   371 ----------------PSSKMTKTAKRRMQAKSKKVISFFKNHRRMLRRQGIEDLLYLA------ 413
                            |:.||:|..|::::.|.|:.....:.     |.|.||::...:
  Rat   243 APPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEK-----RMQEIEEMEKESGPGQKR 302

  Fly   414 -----------ERGLI---------EPITAAMAVSDNLPFIPFGFDG------------------ 440
                       ||.|.         |.:..:.::..:......|.:|
  Rat   303 PNKQEESESPVERPLTENPPNKMTQEKLEESSSIGQDQTLTEHGGEGGAPEINCNGVIGIVNYTA 367

  Fly   441 ------------FMMMSDADCRTVQN--SKLPEMEGMEYKCDRINLCLKS----PE-LFLRYVLD 486
                        ....:|.|.||::.  |.|....|........:.|..|    || :..:..::
  Rat   368 NSNNETLRLKEDLHNANDCDGRTLKQEPSFLSSPNGDSSPSPETDSCTPSGSEVPETMACQASVE 432

  Fly   487 IIKNLDEKELSTQDKRRRFTQASGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIYPID 551
            ....|.:::::...:|.|....||..|.:::..:   |.|...::.|     |..||     |::
  Rat   433 RSLTLTQQDITHLQERIRAHTPSGDEQEREHNGA---LDSKGKFSAG-----NFLIN-----PLE 484

  Fly   552 PANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGT 616
            |.|.| .::||||||||||:.|.|||:||||::||:|||::|:||...|||||.||:.:|||||.
  Rat   485 PKNAE-KLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGD 548

  Fly   617 YLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANIL 681
            |||:.||.. .|..||.|||.|:|..|::|..||..||:|:.|....|.|.:|..|||..|..:|
  Rat   549 YLFEPHSGE-DYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHITKLKPWGLLEVL 612

  Fly   682 IRWYGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYL 722
            :..|.|...::..|.:||:|||:..|..|.:|::.|...:|
  Rat   613 VEKYEWPQEEAAGFTDFLLPMLELMPEKRATAAECLRHPWL 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	212/610 (35%)
Srpk1	NP_001020897.1	Protein Kinases, catalytic domain	70..653	CDD:473864	212/609 (35%)