Protein Alignment CG8565 and srpk1a

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_955944.1
• Gene: srpk1a / 323679
• ZFINID: ZDB-GENE-030131-2399
• Length: 634
• Species: Danio rerio
• Alignment Length: 688
• Identity: 232/688 - (33%)
• Similarity: 335/688 - (48%)
• Gaps: 145/688 - (21%)

  Fly   113 KKRCKQKRRMPSSLSDDGIAGRKPAKINKYSELSYGSESSMPFEMKQQSNDNQNNNDNAEGSGFD 177
            |||.|.|:           :.:|||...:      |:....|...:.|.   |..::...||..:
Zfish    12 KKRAKAKK-----------STKKPAHPPR------GASQQQPPPTETQI---QEPDEEILGSDDE 56

  Fly   178 RQESANEYVIGGYHPVAIGDVFVNRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKE 242
            .||..|:|..||||.|.|||:..::|||.:||||||||||||.:|.|..|:.|:||.|||:.|.|
Zfish    57 EQEDPNDYCKGGYHHVKIGDLLNSKYHVIRKLGWGHFSTVWLAWDIQGKRFVAMKVVKSAEHYTE 121

  Fly   243 TGIDEIMLFSQMSLHD-QHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCFYKGM 306
            |.:|||.|...:...| ....|..||...|.|:|:|.:|.|:|:|.||||.:|||.|.:..|:|:
Zfish   122 TALDEIKLLRSVRNTDPDDPNREMVVQLLDDFKISGVNGTHVCMVFEVLGHHLLKWIIKSNYQGL 186

  Fly   307 PISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSP 371
            |:..:|.|.:|||.||.:||.:|.|||||:||||:|::..|:.||.....|.| :.||  |...|
Zfish   187 PLPCVKSIIRQVLQGLDYLHTKCQIIHTDIKPENILMSVEELYVRRLAAEATE-WQKA--GAPPP 248

  Fly   372 SSKMTKTAKRRMQA----KSKKVISFFKNHRRMLRRQG--IEDLLYLAERGLIEPITAAMAVSDN 430
            |.....||....||    |:||     |..::..:||.  :|..:...|...|.|  ......::
Zfish   249 SGSAVSTAPAPKQAPKMSKNKK-----KKLKKKQKRQAELLEKCIMDLEEMEIGP--EGREEEED 306

  Fly   431 LPFIPFGFDGFMMMSDADCRTVQNSKLPEM----------------EGMEYKCDRINLCL----- 474
            .|..|         ....|..::.:.|.|:                ..:|..|   |.||
Zfish   307 DPESP---------KSPSCAPLRQASLQEIATEDIIMDTRERLTSDASVELNC---NGCLHSSKT 359

  Fly   475 -----------------------------------------KSPELFLRYVLDII---------K 489
                                                     :|||      ||..         :
Zfish   360 QPEEDEQGDLQYGQLLQEDHHNANAGPEDTAQSMYEYCNGAESPE------LDQACYSNGTSGQE 418

  Fly   490 NLDEKELSTQDKRRRFTQASGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIYPIDPAN 554
            .|::.||:|:::.::.|:...|.|.|...:.. :|::.:..                :.|:||.|
Zfish   419 QLEDGELATEEQHQQKTRTRAREQNKDKIKDD-KLSAGSLL----------------VNPLDPLN 466

  Fly   555 NECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLF 619
            .: .::||||||||||:.|.|||:||||::||:|||:||:||...|||||.||:.:|||||.|||
Zfish   467 AD-KIKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLLGSGYNTPADIWSTACMAFELATGDYLF 530

  Fly   620 DTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANILIRW 684
            :.||.. .|:.||.|||.|:|..|.:|..|:..||:|:.|.:..|.|.:|..|||..|.::|:..
Zfish   531 EPHSGE-DYSRDEDHIALIIELLGVVPRKLVLTGKYSKEFFSKKGDLKHITKLKPWGLLDVLMDK 594

  Fly   685 YGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYL 722
            |.|...::..|.:||:|||:..|..|.:|:..|...:|
Zfish   595 YEWPQEEAQTFSDFLLPMLELLPEKRATAADCLRHPWL 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	209/607 (34%)
srpk1a	NP_955944.1	Protein Kinases, catalytic domain	72..632	CDD:473864	209/606 (34%)