Protein Alignment CG8565 and Srpk2

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: XP_038963154.1
• Gene: Srpk2 / 296753
• RGDID: 1305107
• Length: 749
• Species: Rattus norvegicus
• Alignment Length: 794
• Identity: 251/794 - (31%)
• Similarity: 345/794 - (43%)
• Gaps: 220/794 - (27%)

  Fly   102 IEQRAKRPKIC---------------KKRCKQKRRMPSSLSDDGIAGRKPAKINKYSELSYGSES 151
            :|:||.||..|               :|:.|||..:..|::               ||.|..||.
  Rat     1 MERRAARPAGCWPFRPESGGRKERNIRKKIKQKIELLMSVN---------------SEKSSSSER 50

  Fly   152 SMPFEMKQQSND------------------NQNNNDNAEGSGFDRQESANEYVIGGYHPVAIGDV 198
            ..|    ||...                  .....:...||..:.||...:|..||||||.|||:
  Rat    51 PEP----QQKAPLVPPPPPPPPPPPLPDPVPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDL 111

  Fly   199 FVNRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHD-QHKY 262
            |..||||.:|||||||||||||:|.|..|:.|:||.||||.|.||.:|||.|...:...| ....
  Rat   112 FNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN 176

  Fly   263 RSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCFYKGMPISNIKQIAQQVLTGLKFLHE 327
            :..||...|.|:|:|.:|.|:|:|.||||.:|||.|.:..|:|:|:..:|.|.:|||.||.:||.
  Rat   177 KDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHS 241

  Fly   328 ECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLS-----------PSSKMTKTAKR 381
            :|.|||||:||||:|:..:...||.....|.| :.||.....|           |..|::|..|:
  Rat   242 KCKIIHTDIKPENILMCVDGAYVRRMAAEATE-WQKAGAPPPSGSAVSTAPQQKPIGKISKNKKK 305

  Fly   382 RMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDGFMMMSD 446
            :::.|.|:.....:.     |.|.||:|...|||.::|..|.:...|..              .|
  Rat   306 KLKKKQKRQAELLEK-----RLQEIEELEREAERKILEENTTSAEASSE--------------QD 351

  Fly   447 ADCRTVQNSKLPEME---------------------------------GMEYKCDRIN-LCLKSP 477
            .:|:.....|..|:|                                 .:|.:.:.|: ..::||
  Rat   352 GECQPEVKLKEAELEDTTEEETAKDNGEVEDQEEKEDTEKENTEKDEDDVEQELENIDPTWMESP 416

  Fly   478 E--------LFL-------------------RYVLDIIKNLDEKELST----------------- 498
            :        |||                   .|      ||||....:
  Rat   417 KANGHIENGLFLLEQQLEDEEDEEDDCANPEEY------NLDEPNAESDYTYSSSYEQFNGELPN 475

  Fly   499 -QDKRRRF----------------TQASGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLND 546
             |.|...|                ..:.|...|:....|..|..|.....:.||.....|....|
  Rat   476 GQPKSPEFPTPLFSGPLEPVASDSVLSEGSPLTEPEESSPSRDRSRTVSASSTGDLPKTKTRAAD 540

  Fly   547 --IYPIDPANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLL 609
              :.|:||.|.: .:|||||||||||:.|.|||:||||::||::||::||||...|||||.||:.
  Rat   541 LLVNPLDPQNAD-KIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMA 604

  Fly   610 WELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFIN------------- 661
            :|||||.|||:.||.. .|:.||.|||.|:|..|.||.:....||:||.|.|
  Rat   605 FELATGDYLFEPHSGE-DYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLG 668

  Fly   662 ------------------SAGKLCNIETLKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQTNPL 708
                              ..|:|.:|..|||..|.::|:..|||....:.:|.:||:|||:..|.
  Rat   669 KVPRKYAMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPE 733

  Fly   709 SRISASKALESHYL 722
            .|.||.:.|...:|
  Rat   734 KRASAGECLRHPWL 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	222/669 (33%)
Srpk2	XP_038963154.1	Protein Kinases, catalytic domain	103..>291	CDD:473864	91/188 (48%)
		2A1904	<338..417	CDD:273344	11/92 (12%)
		Protein Kinases, catalytic domain	<538..747	CDD:473864	88/210 (42%)