Protein Alignment CG8565 and Srpk3

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: XP_006229620.1
• Gene: Srpk3 / 293854
• RGDID: 727856
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 636
• Identity: 235/636 - (36%)
• Similarity: 314/636 - (49%)
• Gaps: 84/636 - (13%)

  Fly   112 CKKRCKQKRRMPSSLSDDGIAGRKPAKINKYSELSYGSESS-------MPFEMKQQSNDNQNNND 169
            |.:......||  |.|..|..|......:..|:.|.|.|||       .|.....|
  Rat    15 CTRALGCDTRM--SASAGGSGGMDCGGSSSSSQTSCGPESSSSELAPATPAPRLLQ--------- 68

  Fly   170 NAEGSGFDRQESANEYVIGGYHPVAIGDVFVNRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVS 234
            ...||..:.||...:|..|||:||.|||:|..||||.:|||||||||||||:|.|..|:.|:||.
  Rat    69 GLLGSDDEEQEDPKDYCKGGYYPVKIGDLFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVV 133

  Fly   235 KSAQVYKETGIDEIMLFSQMSLHD-QHKYRSHVVGFYDFFEITGPHG--RHICLVLEVLGDNLLK 296
            |||..|.||.:|||.|...:...| ....|..:|...|.|.|:|.:|  ..:|:||||||..|||
  Rat   134 KSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVRPDVCMVLEVLGHQLLK 198

  Fly   297 VIERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVY 361
            .|.:..|:|:|:..:|.|.:|||.||.:||.:|.|||||:||||:||...:..:|   :.|.|..
  Rat   199 WIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIR---RLAAEAT 260

  Fly   362 LKANEGKLSPSSKMTKTAKRRMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAER----GLIEPIT 422
            .....|...||.....||.:.:....|    ..||.|:.:||:..:....|.||    ..:|.:.
  Rat   261 EWQQSGAQPPSRSTVSTAPQEVLQTGK----LSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAME 321

  Fly   423 AAMAVSDNLPFIPFGFDGFMMMSDADCRTVQNSKLPEMEGMEYKCDRI--NLCLKSPELFLRYVL 485
            ||                 :...|:..|..|.|......|...:..|.  :....||
  Rat   322 AA-----------------VQTEDSSSRLEQGSGSTSSSGCHPEGTRAGPSPASSSP-------- 361

  Fly   486 DIIKNLDEKELSTQDKRRRFTQASG-RGQTKKNAR-SRLRLASNAAYTTGT-------GWRSNRK 541
              :....|:.||..      :|.|| .|.....|. |.|..:||...|.|.       | .||..
  Rat   362 --VPTGGERSLSPS------SQTSGFSGSLFSTASCSVLSGSSNQRETGGLLSPSTPFG-ASNLL 417

  Fly   542 INLNDIYPIDPANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVA 606
            :|     |::|.|.: .:::|||||||||:.|.|||:||||::|||:||::||.|...|||||.|
  Rat   418 VN-----PLEPQNAD-KIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTA 476

  Fly   607 CLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIET 671
            |:.:|||||.|||:.||.. .|:.||.|||.|||..|.||......|::||.|.|..|:|.:|..
  Rat   477 CMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHN 540

  Fly   672 LKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYL 722
            ||...|..:|:..|.|...|:|:|..||:||::..|..|.||:..|:..:|
  Rat   541 LKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	211/547 (39%)
Srpk3	XP_006229620.1	Protein Kinases, catalytic domain	91..591	CDD:473864	211/547 (39%)