Protein Alignment CG8565 and Mapk3

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_036082.1
• Gene: Mapk3 / 26417
• MGIID: 1346859
• Length: 380
• Species: Mus musculus
• Alignment Length: 648
• Identity: 120/648 - (18%)
• Similarity: 188/648 - (29%)
• Gaps: 324/648 - (50%)

  Fly   173 GSGFDRQESANEYVIGGYHPVAIGDVFV---------NRYHVFKKLGWGHFSTVWLCYD-TQMDR 227
            |.|.:.:.:|      |..||..|:|.|         .||...:.:|.|.:..|...|| .:..|
Mouse    10 GGGGEPRGTA------GVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTR 68

  Fly   228 YCAVKVSK-SAQVYKETGIDEIMLFSQMSLHDQHKYRSHVVGFYDFFEI-TGPHGRHICLVLEVL 290
            ....|:|. ..|.|.:..:.||    |:.|..:|:   :|:|..|.... |....|.:.:|.:::
Mouse    69 VAIKKISPFEHQTYCQRTLREI----QILLRFRHE---NVIGIRDILRAPTLEAMRDVYIVQDLM 126

  Fly   291 GDNLLKVIERCFYKGMPISN--IKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTE 353
            ..:|.|::     |...:||  |.....|:|.|||::| ...::|.||||.|:|:
Mouse   127 ETDLYKLL-----KSQQLSNDHICYFLYQILRGLKYIH-SANVLHRDLKPSNLLI---------- 175

  Fly   354 IKTAIEVYLKANEGKLSPSSKMTKTAKRRMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAERGLI 418
                                                                             
Mouse   176 ----------------------------------------------------------------- 175

  Fly   419 EPITAAMAVSDNLPFIPFGFDGFMMMSDADCRTVQNSKLPEMEGMEYKCDRINLCLKSPELFLRY 483
                                                                             
Mouse   176 ----------------------------------------------------------------- 175

  Fly   484 VLDIIKNLDEKELSTQDKRRRFTQASGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIY 548
                                                                             
Mouse   176 ----------------------------------------------------------------- 175

  Fly   549 PIDPANNECDVRVKIADLGNACYF---HHH---FTDDIQTKEYRALEVILGA-GYCETADIWSVA 606
                 |..||  :||.|.|.|...   |.|   .|:.:.|:.|||.|::|.: ||.::.|||||.
Mouse   176 -----NTTCD--LKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVG 233

  Fly   607 CLLWELATGTYLFDTHSKRGKYNLDEV-HIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIE 670
            |:|.|:.:...:|.     ||:.||:: ||..|:             |..|:..:|     |.|.
Mouse   234 CILAEMLSNRPIFP-----GKHYLDQLNHILGIL-------------GSPSQEDLN-----CIIN 275

  Fly   671 TLKPLKLANIL--------IRWYGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYLCNIAL 727
                :|..|.|        :.|.....:..::.::.|..||..||..||:..:||...||
Mouse   276 ----MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYL----- 331

  Fly   728 PGIDIDSYYYYSVREIKDCTHTKSERNSDEDSSSCSSIDSSEFSSD-EVCYEDDVNEEDIKKL 789
                 :.||        |.|        ||      .:....|:.| |:   ||:.:|.:|:|
Mouse   332 -----EQYY--------DPT--------DE------PVAEEPFTFDMEL---DDLPKERLKEL 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	100/559 (18%)
Mapk3	NP_036082.1	STKc_ERK1_2_like	37..371	CDD:270839	111/615 (18%)
		TXY	203..205		1/1 (100%)