Protein Alignment CG8565 and Srpk2

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: XP_011248053.1
• Gene: Srpk2 / 20817
• MGIID: 1201408
• Length: 750
• Species: Mus musculus
• Alignment Length: 788
• Identity: 256/788 - (32%)
• Similarity: 353/788 - (44%)
• Gaps: 207/788 - (26%)

  Fly   102 IEQRAKRPKIC---------------KKRCKQKRRMPSSLSDDGIAGRKPAKINKYSELSYGSES 151
            :|:||.||..|               :|:.|||..:..|::               ||.|..||.
Mouse     1 MERRAARPAGCWPFRPESGGRKERNIRKKIKQKTELLMSVN---------------SEKSSSSER 50

  Fly   152 SMPFEMKQQS----------------NDNQNNNDNAE--GSGFDRQESANEYVIGGYHPVAIGDV 198
            ..|    ||.                .|........|  ||..:.||...:|..||||||.|||:
Mouse    51 PEP----QQKAPLVPPPPPPPPPPPLPDPAPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDL 111

  Fly   199 FVNRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHD-QHKY 262
            |..||||.:|||||||||||||:|.|..|:.|:||.||||.|.||.:|||.|...:...| ....
Mouse   112 FNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPN 176

  Fly   263 RSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCFYKGMPISNIKQIAQQVLTGLKFLHE 327
            :..||...|.|:|:|.:|.|:|:|.||||.:|||.|.:..|:|:|:..:|.|.:|||.||.:||.
Mouse   177 KDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHS 241

  Fly   328 ECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLS-----------PSSKMTKTAKR 381
            :|.|||||:||||:|:..::..||.....|.| :.||.....|           |..|::|..|:
Mouse   242 KCKIIHTDIKPENILMCVDDAYVRRMAAEATE-WQKAGAPPPSGSAVSTAPQQKPIGKISKNKKK 305

  Fly   382 RMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAERGLIEP-ITAAMAVSDNLPFIPFGFDG----- 440
            :::.|.|:.....:.     |.|.||:|...|||.::|. ||:|.|..:..       ||
Mouse   306 KLKKKQKRQAELLEK-----RLQEIEELEREAERKILEENITSAEASGEQQ-------DGEYQPE 358

  Fly   441 -FMMMSDADCRTVQNSKLP--EMEGMEYKCD----------------------------RINLCL 474
             .:..:|.:..|.:.:...  |:|..|.|.|                            :.|..:
Mouse   359 VTLKAADLEDTTEEETAKDNGEVEDQEEKEDAEKENAEKDEDDVEQELANLDPTWVESPKANGHI 423

  Fly   475 KSPELFLRYVL-------DIIKNLDEKELSTQDKRRRFTQASG---------RGQTK-------- 515
            ::....|...|       |...|.:|..|...:....:|.:|.         .||.|
Mouse   424 ENGPFSLEQQLEDEEDDEDDCANPEEYNLDEPNAESDYTYSSSYEQFNGELPNGQHKTSEFPTPL 488

  Fly   516 ----------------------------KNARSRLRLASNAAYTTGTGWRSNRKINLND--IYPI 550
                                        .:.|||...||:      ||.....|....|  :.|:
Mouse   489 FSGPLEPVACGSVISEGSPLTEQEESSPSHDRSRTVSASS------TGDLPKTKTRAADLLVNPL 547

  Fly   551 DPANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATG 615
            ||.|.: .:|||||||||||:.|.|||:||||::||::||::||||...|||||.||:.:|||||
Mouse   548 DPRNAD-KIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATG 611

  Fly   616 TYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFIN------------------- 661
            .|||:.||.. .|:.||.|||.|:|..|.||.:....||:||.|.|
Mouse   612 DYLFEPHSGE-DYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRDHIALIIELLGKVPRKY 675

  Fly   662 ------------SAGKLCNIETLKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQTNPLSRISAS 714
                        ..|:|.:|..|||..|.::|:..|||....:.:|.:||:|||:..|..|.||.
Mouse   676 AMLGKYSKEFFTRKGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAG 740

  Fly   715 KALESHYL 722
            :.|...:|
Mouse   741 ECLRHPWL 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	225/663 (34%)
Srpk2	XP_011248053.1	Protein Kinases, catalytic domain	103..>291	CDD:473864	91/188 (48%)
		2A1904	<338..418	CDD:273344	14/86 (16%)
		Protein Kinases, catalytic domain	<537..748	CDD:473864	88/212 (42%)