Protein Alignment CG8565 and SRPK

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: XP_061498458.1
• Gene: SRPK / 1276029
• VectorBaseID: AGAMI1_013127
• Length: 794
• Species: Anopheles gambiae
• Alignment Length: 682
• Identity: 236/682 - (34%)
• Similarity: 342/682 - (50%)
• Gaps: 100/682 - (14%)

  Fly   125 SLSDDG---IAGRKPAKINKYSELSYGSESSMPFEMKQQSNDNQNNNDNAEG--SGFDRQESANE 184
            |:|..|   :.||:.:|..........:.:|...|..:|..|.     :|:|  |..:.||...:
Mosquito   127 SVSSGGPAELVGRRGSKSAGQPHHHLDTTTSSSNETIEQDGDR-----DADGYTSEEEEQECRED 186

  Fly   185 YVIGGYHPVAIGDVFVNRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIM 249
            |..||||||.:||:|:.||||.:||||||||||||.:|.:..||.|:|:.||||.:.:|..|||.
Mosquito   187 YCRGGYHPVKLGDLFLQRYHVIRKLGWGHFSTVWLSWDLEEKRYVALKIVKSAQHFSDTAKDEIH 251

  Fly   250 LFSQMSLHD-QHKYRSHVVGFYDFFEITGPHGRHICLVLEVLGDNLLKVIERCFYKGMPISNIKQ 313
            :...::..| ....|:.||...:.|.|||.:|.|||:|.||||.||||:|.:..|:|:|::|:|.
Mosquito   252 ILKSITNADPADPKRNKVVQLLNDFRITGVNGTHICMVFEVLGHNLLKLIMKSNYRGIPLANVKS 316

  Fly   314 IAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLS-------- 370
            |.:|||.||.:||.:|.|||||:||||||:..||..||.....|.|::....:..:|
Mosquito   317 IIRQVLEGLDYLHTKCKIIHTDIKPENVLVCVNESYVRKLACEATEMHAMGCKLPISLISAAPPQ 381

  Fly   371 -----PSSKMTKTAKRRMQAKSK---KVISFFKNHRRMLR------------------------- 402
                 .|..|:|..|::::.|:|   ::|.....|.:.|.
Mosquito   382 FQEQPMSQNMSKAKKKKLKRKAKMQHELIRQQMEHIQQLEFGAPVAVDGASSGSGGPAAGLPLEN 446

  Fly   403 --RQGIED---LLYLAERG------LIEPITAA---MAVSDNLPFIPF-----GFDG--FMMMSD 446
              .:|:|.   ||.||..|      .::.:|.|   .|.....|..|.     |.:.  .::...
Mosquito   447 GTAEGMESGKPLLALAAEGAGGGGATLKGVTTAGSNTAAGTGTPNSPLERKEAGGEARRLLVNGT 511

  Fly   447 ADCRTVQNSKLPEMEGMEYKC------------DRINLCLKSPELFLRYVLDIIKNLDEKELSTQ 499
            |:..|....|         :|            ||..|...:..|......:...:.:..::...
Mosquito   512 AEATTTAGGK---------ECVAEAGTPSSGDEDRPTLTPSASTLSSPSSSEAASSNNNDDVPGD 567

  Fly   500 DKRRRFTQASGRGQTKKNARSRLRLASNAAYTTGTGW---RSNRKINLNDIYPIDPANNECDVRV 561
            .|........|..:.:::|:|..:.:|::..|:.:..   .|.|||..:.....|.|...||:.|
Mosquito   568 RKSPTARVHDGDERRERDAKSPEKPSSSSLVTSSSKLDISESVRKILSSVQESKDAAFEVCDIDV 632

  Fly   562 KIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRG 626
            |||||||||:...|||:||||::||:||||:||||..:|||||.||:.:|||||.|||:..|  |
Mosquito   633 KIADLGNACWVDKHFTEDIQTRQYRSLEVIIGAGYDTSADIWSTACMAFELATGDYLFEPFS--G 695

  Fly   627 K-YNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANILIRWYGWRTR 690
            | |..|:.|||.|:|..|.||..:...||:|.:..||.|.|.||..|||..|.::||..|.|...
Mosquito   696 KDYCRDDDHIAHIIELLGPIPKRIALSGKNSSHAFNSKGLLKNISGLKPWGLVDVLIEKYEWSDE 760

  Fly   691 QSTEFVNFLMPMLQTNPLSRISASKALESHYL 722
            .:.||.:||.|||..:|.:|.:|:..|...:|
Mosquito   761 DAFEFSDFLKPMLDYDPRTRATAADCLRHSWL 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	215/608 (35%)
SRPK	XP_061498458.1	None