Protein Alignment CG8565 and mapk6

DIOPT Version :10

• Sequence 1: NP_573080.1
• Gene: CG8565 / 32538
• FlyBaseID: FBgn0030697
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: XP_002936385.1
• Gene: mapk6 / 100494114
• XenbaseID: XB-GENE-478419
• Length: 720
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 113/638 - (17%)
• Similarity: 185/638 - (28%)
• Gaps: 311/638 - (48%)

  Fly   201 NRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVK--VSKSAQVYKETGIDEIMLFSQMSLHDQHKYR 263
            :||...|.||:|....|:...|...|:..|||  |....|..|. .:.||.:..::. ||
 Frog    18 SRYMDLKPLGYGGNGLVFSAVDNDCDKRVAVKKIVLTDPQSVKH-ALREIKIIRRLD-HD----- 75

  Fly   264 SHVVGFYDFFEITGPHGRHI-----------C--LVLEVLGDNLLKVIERCFYKGMPI--SNIKQ 313
                .....|||.||:||.:           |  :|.:.:..:|.|::|:     .|:  .:.:.
 Frog    76 ----NIVKVFEILGPNGRQLTDDVSSLTELNCVYIVQDYMETDLAKLLEQ-----GPLREEHARL 131

  Fly   314 IAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSPSSKMTKT 378
            ...|:|.|||::| ...::|.||||.|:.:
 Frog   132 FMYQLLRGLKYIH-SANVLHRDLKPANLFI----------------------------------- 160

  Fly   379 AKRRMQAKSKKVISFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDGFMM 443
                                                                             
 Frog   161 ----------------------------------------------------------------- 160

  Fly   444 MSDADCRTVQNSKLPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKNLDEKELSTQDKRRRFTQA 508
                                                                             
 Frog   161 ----------------------------------------------------------------- 160

  Fly   509 SGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIYPIDPANNECDVRVKIADLGNA---- 569
                                                         |.| |:.|||.|.|.|
 Frog   161 ---------------------------------------------NTE-DLVVKIGDFGLARIMD 179

  Fly   570 -CYFHH-HFTDDIQTKEYRALEVILGA-GYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLD 631
             .|.|. |.::.:.||.||:..::|.. .|.:..|:|:..|:..|:.||..||     .|.:.|:
 Frog   180 PHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLF-----AGAHELE 239

  Fly   632 E----------VHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLK--LANILIRW 684
            :          ||.....|....||.|:       :|.::        |..|||.  |..|
 Frog   240 QMQLILESIPVVHEEDRQELLNVIPVYI-------KNDMS--------EPHKPLTQLLPGI---- 285

  Fly   685 YGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYLCNIALPGID--IDSYYYYSVREIKDC- 746
                   |:|.::||..:|..:|:.|::|.:||...|:...:.| :|  |.|:.::...|:.|.
 Frog   286 -------SSEALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFP-MDEPISSHPFHIEDEVDDIL 342

  Fly   747 ----THTKS---ERNSDEDSSSCSSIDSSEFSSDEV-----CYEDDVNEEDIK 787
                :|::.   ||..:.|.|.......:.|..|||     ...|..::|:::
 Frog   343 LMDDSHSQVYNWERYHESDFSDHDWPIHNNFEVDEVQRDPRALSDGSDDEEVQ 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8565	NP_573080.1	Protein Kinases, catalytic domain	192..722	CDD:473864	95/556 (17%)
mapk6	XP_002936385.1	STKc_MAPK4_6	14..355	CDD:143359	103/596 (17%)