Protein Alignment sd and Tead2

DIOPT Version :10

• Sequence 1: NP_001368984.1
• Gene: sd / 32536
• FlyBaseID: FBgn0003345
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_035695.1
• Gene: Tead2 / 21677
• MGIID: 104904
• Length: 445
• Species: Mus musculus
• Alignment Length: 451
• Identity: 235/451 - (52%)
• Similarity: 285/451 - (63%)
• Gaps: 82/451 - (18%)

  Fly    46 WTPVNAGPPGALGSADTNGSMVDSKNLDVGDMSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPP 110
            ||....|.....|.::..|          ||        .|.||||||||||||||||||:||||
Mouse    16 WTGSEEGSEEGTGGSEGVG----------GD--------GSPDAEGVWSPDIEQSFQEALAIYPP 62

  Fly   111 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIK------- 168
            |||||||||||||||||||||||||||||||||||||||||||||||||.||||:|:|
Mouse    63 CGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDK 127

  Fly   169 ---------------------------------VQFWQPGLQPSTS-QDIKPFPQPPYPAGKTST 199
                                             .|||.....|..: .|:|||.|.|:....|..
Mouse   128 AFQTMATMSSAQLISAPSLQAKLGPSGPQATELFQFWSGSSGPPWNVPDVKPFSQAPFSVSLTPP 192

  Fly   200 AVSGDETGIPP----SQLP--------WEGRAIATHKFRLLEFTAFMEIQRDEI--YHRHLFVQL 250
            |  .|..|..|    |.||        |:.||:.|.:.:|:||:||:| ..|.:  :.|||||.:
Mouse   193 A--SDLPGYEPPPALSPLPPPAPSPPAWQARALGTARLQLIEFSAFVE-PPDAVDSFQRHLFVHI 254

  Fly   251 GGK-PSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLN-----TDLTTGS 309
            ..: ||...|.||:||:|||:||||||.|||::||::||.:||:|||.|||||     .:..:..
Mouse   255 SQQCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSAEEAGSSG 319

  Fly   310 ETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINF 374
            ..|.||||:|||||.|.:.|.||:.|||||||||||||:|.::||:.|:|||:.|||||||::||
Mouse   320 GGGGFYGVSSQYESRELMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNF 384

  Fly   375 IQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIKE 435
            :.||:.|||||||||||||||||||:..|:|||.|||.||||||:....|..:|||||:::
Mouse   385 LHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQYHIYRLVRD 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sd	NP_001368984.1	TEA	88..155	CDD:128703	65/66 (98%)
		YBD	224..432	CDD:435993	126/215 (59%)
Tead2	NP_035695.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..47		14/48 (29%)
		TEA	40..107	CDD:128703	65/66 (98%)
		Transcriptional activation. /evidence=ECO:0000255	172..445		146/275 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..217		7/27 (26%)
		YBD	227..442	CDD:435993	126/215 (59%)