DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sd and tead1

DIOPT Version :9

Sequence 1:	NP_001368984.1	Gene:	sd / 32536	FlyBaseID:	FBgn0003345	Length:	747	Species:	Drosophila melanogaster
Sequence 2:	XP_031756267.1	Gene:	tead1 / 100158507	XenbaseID:	XB-GENE-5909149	Length:	439	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	260/442 - (58%)
Similarity:	301/442 - (68%)	Gaps:	86/442 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 MSDDEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGK 141
            |||........||||||||||||||||||:|||||||||||||||||||||||||||||||||||
Frog     1 MSDSADKPMDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGK 65

  Fly   142 TRTRKQVSSHIQVLARRKLREIQAKIKVQ------------------------------------ 170
            ||||||||||||||||:|:|||||.|||.
Frog    66 TRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSRDFHSKLKVTNMDQTAKDKALQHMA 130

  Fly   171 --------------------------------FWQPGL----QPSTSQDIKPFPQPPYPAGKTST 199
                                            :| ||:    ||.:|||:|||.|..||...::|
Frog   131 AMSSAQIVSATAIHNKLGLPGIPRPAFPAAPGYW-PGMIQTGQPGSSQDVKPFAQQAYPIQPSAT 194

  Fly   200 A-------VSGDETGIPP-SQLP-WEGRAIATHKFRLLEFTAFMEIQRD-EIYHRHLFVQLG-GK 253
            |       |||.|...|| |.:| |:||:|.|.|.||:||:||:|.||| :.|::||||.:| ..
Frog   195 APIPGTYSVSGFEPAPPPASSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDAYNKHLFVHIGQAN 259

  Fly   254 PSFSDPLLETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVT 318
            .|:||||||:||||||:||||||.||||:|:.|||||||:|||.|||||.::.  .:||.|||||
Frog   260 HSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQ--DDTGAFYGVT 322

  Fly   319 SQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPE 383
            |||||:||:.:.|||.|||||||||||||:||:|.||.|:||||.||||||||||||.|||:|||
Frog   323 SQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPE 387

  Fly   384 RYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHIYRLIKE 435
            :|||||||||||||.|:..|:|||||||:|.||||:....|..||||||:||
Frog   388 KYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHIYRLVKE 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sd	NP_001368984.1	TEA	88..155	CDD:128703	65/66 (98%)
sd	NP_001368984.1	YBD	224..432	CDD:407601	146/209 (70%)
tead1	XP_031756267.1	TEA	12..79	CDD:128703	65/66 (98%)
tead1	XP_031756267.1	YBD	228..436	CDD:407601	146/209 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	299	1.000	Domainoid score	I1426
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2418
Inparanoid	1	1.050	466	1.000	Inparanoid score	I1502
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D355519at33208
OrthoFinder	1	1.000	-	-		FOG0001013
OrthoInspector	1	1.000	-	-		otm49111
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X674
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060