DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8509 and Ptpa

DIOPT Version :9

Sequence 1:	NP_573079.1	Gene:	CG8509 / 32535	FlyBaseID:	FBgn0030696	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_001102047.1	Gene:	Ptpa / 362102	RGDID:	1308354	Length:	323	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	99/313 - (31%)
Similarity:	169/313 - (53%)	Gaps:	25/313 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PVKQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFPVTEQMRRLSEIFDGLDHLIVE 91
            |.|::.::.|:.:|.|||||.|.|.:|...::.::|.:||..:.|:|.:.:|..:.|.||..|.|
  Rat    26 PKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKVSEAIEKLVALLDTLDRWIDE 90

  Fly    92 HTPKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVN-CKHINELGQYLRRSFGNGNT 155
            ..|..:.|    .||   :||||||..::.|...:.:...|..| ...:.|:..||:.:.||...
  Rat    91 TPPVDQPS----RFG---NKAYRTWYAKLDQEAENLVATVIPTNLAAAVPEVAVYLKEAVGNSTR 148

  Fly   156 LDFGPANELMFLFFLCGLFRAGILLAKDTVAAALMLFNRYVNVVRRLISTYGLTIAKDPACT--- 217
            :|:|..:|..|..|||.|.:.|:|...|.||....:|:||:.|:|:|..||.:    :||.:
  Rat   149 IDYGTGHEAAFAAFLCCLCKIGVLRVDDQVAIVFKVFDRYLEVMRKLQKTYRM----EPAGSQGV 209

  Fly   218 --IEDYYFLPYLWGAAQLSVDSP-FSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGPLSRVAL 279
              ::|:.|||::||::|| :|.| ..|......|.:....:|:|.|:.|..:.:.::||.:..:.
  Rat   210 WGLDDFQFLPFIWGSSQL-IDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGPFAEHSN 273

  Fly   280 QLWSILSIPTWPQVYRGLERNYIDHVLSSFGTVEQAIFCELMSFEAVVPIMPL 332
            |||:|.::|:|.:|.:||.|.|....|..|..::.      ..|.:::||.|:
  Rat   274 QLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQH------FKFGSLLPIHPV 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8509	NP_573079.1	PTPA	27..324	CDD:281137	95/303 (31%)
Ptpa	NP_001102047.1	PTPA	26..316	CDD:281137	96/307 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352264
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5057
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54183
OrthoDB	1	1.010	-	-		D1165705at2759
OrthoFinder	1	1.000	-	-		FOG0002736
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.820