DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PGRP-LE and mig-39

DIOPT Version :9

Sequence 1:	NP_001245695.1	Gene:	PGRP-LE / 32534	FlyBaseID:	FBgn0030695	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_498871.3	Gene:	mig-39 / 185686	WormBaseID:	WBGene00018369	Length:	943	Species:	Caenorhabditis elegans

Alignment Length:	300	Identity:	62/300 - (20%)
Similarity:	114/300 - (38%)	Gaps:	72/300 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TEEEEDADQNTSEEISTMTLGTQI-ATKKHSIISDTIR---DLMNSINSIQTLGNVNISNSTNVH 103
            ||.:.:...|::......:|.:|: |:||.:::.|..:   |:.....|:...|....|..|.|.
Worm   457 TESQYEHIVNSTSHKLIQSLKSQLSASKKLNLLLDITKITADISRVTVSVALTGGAGNSYETQVI 521

  Fly   104 IGNVTNINGN----IQIIADGLTQNRRDRRHVSPPRDNAPKTPTHFEDDYQDESEERVRSDVFIR 164
            :....|||||    :..:.:.:.|:    .::||...|                 ..:.|.:...
Worm   522 LLAFRNINGNQSEDLTAVFEKVLQD----YNISPSSIN-----------------RVICSGLNEL 565

  Fly   165 RQKFKIPKELSAIIPR-----SSWLAQKPMDEPLP---LQLPVKYVVILHTATESSE--KRAINV 219
            .:..::||::.:...|     .|||...|..|.|.   ..:.|.|:.:......:|:  |....|
Worm   566 AEPAELPKQMDSFSSRLANCFKSWLETSPTVEVLKKNVYAMLVSYLTVPAAIQLASQMLKAKFEV 630

  Fly   220 RLIRDMQCFHIESRGWNDIAYNFLVGCDGNIY----EG------RGW-KTVGAHTLGYNRISLGI 273
            .|   .:.||:       |..:.:...|  ||    ||      |.| |..|.|.|    :::..
Worm   631 PL---TEPFHV-------IVEHLVAHRD--IYQMNMEGITLISEREWNKVTGIHHL----MNIFK 679

  Fly   274 SFIGCFMKELPTAD----ALNMCRNLLARGVED-GHISTD 308
            .|: .:..::.|.|    .:...:|:|.:.:.. |.|.:|
Worm   680 PFM-TYSTDMTTVDTVIPTIVQIQNVLEKDIYHLGDIGSD 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LE	NP_001245695.1	PGRP	175..317	CDD:128941	34/159 (21%)
mig-39	NP_498871.3	Dimer_Tnp_hAT	<866..>902	CDD:283379
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910