Protein Alignment PGRP-LE and PGLYRP3

DIOPT Version :9

• Sequence 1: NP_001245695.1
• Gene: PGRP-LE / 32534
• FlyBaseID: FBgn0030695
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: XP_011507420.1
• Gene: PGLYRP3 / 114771
• HGNCID: 30014
• Length: 377
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 95/305 - (31%)
• Similarity: 152/305 - (49%)
• Gaps: 59/305 - (19%)

  Fly    69 KKHSIISDTIRDLMNSINSIQTLG------NVNISNSTNVHIGNVTNING-------NIQI---- 116
            ::.|:.|..:|.|.:  :|:.|:|      |..:.:...|:.|...||.|       ||.:
Human    94 QQQSVCSQMLRGLQS--HSVYTIGWCDVAYNFLVGDDGRVYEGVGWNIQGLHTQGYNNISLGIAF 156

  Fly   117 ---------------IADGLTQNRRDRRHVSPPRDNAPKTPTHFEDDYQDESEERVRSDVFIRRQ 166
                           .|:||......:.|:| ||...|..               ::.:..:..|
Human   157 FGNKIGSSPSPAALSAAEGLISYAIQKGHLS-PRYIQPLL---------------LKEETCLDPQ 205

  Fly   167 KFKIPKELSA-IIPRSSWLAQK---PMDEPLPLQLPVKYVVILHTATESSEKRAINVRLIRDMQC 227
            ...:|:::.. ||.||:|.|::   |     .:.||.|||:|:|||..|.........::|::|.
Human   206 HPVMPRKVCPNIIKRSAWEARETHCP-----KMNLPAKYVIIIHTAGTSCTVSTDCQTVVRNIQS 265

  Fly   228 FHIESRGWNDIAYNFLVGCDGNIYEGRGWKTVGAHTLGYNRISLGISFIGCFMKELPTADALNMC 292
            ||:::|.:.||.|:||||.||.:|||.||...|:||.|:|.|:|||:|||.|:::.|.|.||...
Human   266 FHMDTRNFCDIGYHFLVGQDGGVYEGVGWHIQGSHTYGFNDIALGIAFIGYFVEKPPNAAALEAA 330

  Fly   293 RNLLARGVEDGHISTDYRLICHCQCNSTESPGRRLYEEIQTWPHF 337
            ::|:...|.:|:::.:|.|:.|....:..|||:.||..|.|||||
Human   331 QDLIQCAVVEGYLTPNYLLMGHSDVVNILSPGQALYNIISTWPHF 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-LE	NP_001245695.1	PGRP	175..317	CDD:128941	59/145 (41%)
PGLYRP3	XP_011507420.1	PGRP	57..195	CDD:128941	23/103 (22%)
		PGRP	215..355	CDD:128941	59/144 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7191
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.800