DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15602 and Hgs

DIOPT Version :9

Sequence 1:	NP_001285298.1	Gene:	CG15602 / 32533	FlyBaseID:	FBgn0030694	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	XP_038942636.1	Gene:	Hgs / 56084	RGDID:	69225	Length:	860	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	61/312 - (19%)
Similarity:	102/312 - (32%)	Gaps:	113/312 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CFGCGRKYGLFCKEYGCPNCGYSFCSKCLKRPMPVPRHA-GKVHNVCLICYDKLSKLQASADAEK 66
            |..|..::|:..:::.|..||..||.||..:...:|:.. .|...||..||::|:|   .|:.:.
  Rat   228 CHRCRVQFGVVTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNK---KAEGKA 289

  Fly    67 VIDCDALPGIL---VTKMNLAPPSKSSDGADALFNDSLPVEELPQALV----------------- 111
            ....:..|..|   :::.:..||.:..   .||..:    |||..||.
  Rat   290 ASTTELPPEYLTSPLSQQSQLPPKRDE---TALQEE----EELQLALALSQSEAEEKERMRQKST 347

  Fly   112 -------------------------PSSSSSPHSKDHKDHIDENLDSELTKRMQDYKRVDATDDE 151
                                     |.:||:|.::|    ||..|...|.:...:.|:.:|....
  Rat   348 YTAHPKSEPAPLASSAPPAGSLYSSPVNSSAPLAED----IDPELARYLNRNYWEKKQEEARKSP 408

  Fly   152 IRTRLANLT------GMPHTKSYDKKDLLLSTDQRNDQEKMRDLLAQFVDEAQLDQNISRQRDDS 210
            ..:....||      |..||                        ....:.||.|.:..|:
  Rat   409 TPSAPVPLTEPAAQPGEGHT------------------------APNSMVEAPLPETDSQ----- 444

  Fly   211 ISDIERRLRALRDTPVDSDACPSRSQMESIADNEEDDETL---LQNILKKYV 259
                          |:.|.:.|...|.:: .::||..|..   |||.:..:|
  Rat   445 --------------PITSCSGPFSEQYQN-GESEESHEQFLKALQNAVSTFV 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15602	NP_001285298.1	PHD_SF	2..52	CDD:304600	14/49 (29%)
Hgs	XP_038942636.1	VHS_Hrs	68..205	CDD:340771
		FYVE_Hrs	221..281	CDD:277260	16/52 (31%)
		PLN03209	<283..441	CDD:178748	32/195 (16%)
		GAT_Hrs	467..562	CDD:410592	5/15 (33%)
		G_path_suppress	560..809	CDD:406402
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1818
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900