DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8974 and Pex10

DIOPT Version :9

Sequence 1:	NP_573076.1	Gene:	CG8974 / 32532	FlyBaseID:	FBgn0030693	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001035866.1	Gene:	Pex10 / 668173	MGIID:	2684988	Length:	324	Species:	Mus musculus

Alignment Length:	133	Identity:	35/133 - (26%)
Similarity:	53/133 - (39%)	Gaps:	23/133 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 TSIPTNSTASELKKSNTSYSFTG------DYLSGGNKADLKGGYPFGGTDTDTKANEKDKEKEHT 117
            |.:.|.....|.:|:.|||...|      ..||.|.:.     |.|.......|.....:...|.
Mouse   197 TYLRTRRLPGEDQKARTSYGLLGLISLLHLVLSMGLRL-----YSFRQKQRARKEWRLHRNLSHR 256

  Fly   118 ADDSLYE--------CNICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCPVCKAAVDKDKV 174
            . .||.:        |.:||:..:.:..:.|||||||.|:.:|..|:..   ||:|:......|:
Mouse   257 R-SSLEDRAVCRTPLCTLCLEERRHSTATPCGHLFCWECITEWCNTKTE---CPLCREKFPPQKL 317

  Fly   175 IPL 177
            :.|
Mouse   318 VYL 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8974	NP_573076.1	RING	124..169	CDD:238093	16/52 (31%)
Pex10	NP_001035866.1	Pex2_Pex12	16..215	CDD:282595	5/17 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	119..139
		zf-RING_2	271..309	CDD:290367	15/40 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930