Protein Alignment CG8974 and RNF5

DIOPT Version :9

• Sequence 1: NP_573076.1
• Gene: CG8974 / 32532
• FlyBaseID: FBgn0030693
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_008844.1
• Gene: RNF5 / 6048
• HGNCID: 10068
• Length: 180
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 90/183 - (49%)
• Similarity: 113/183 - (61%)
• Gaps: 24/183 - (13%)

  Fly   107 ANEKD-----KEKEHTADDSLYECNICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCPVCK 166
            |.|:|     ..:|.....:.:||||||:||::||||:||||:|||||||||.|||.|:.|||||
Human     4 AEEEDGGPEGPNRERGGAGATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPERQECPVCK 68

  Fly   167 AAVDKDKVIPLYGRNSTHQEDPRNKVPPRPAGQRTEPDPVPGFPGFGFGDGFHMSFGIGAFPFGF 231
            |.:.::||:|||||.|...:|||.|.||||.|||..|:...||..||...|||.|||:|||||||
Human    69 AGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDTGGFHFSFGVGAFPFGF 133

  Fly   232 ITSTLNFGEPRPPAANRGT----------RQYEDEQTLSKLFSYLAVVWILWL 274
            .|:..|..||    ..|||          ..::|     .||.:||:.:..||
Human   134 FTTVFNAHEP----FRRGTGVDLGQGHPASSWQD-----SLFLFLAIFFFFWL 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8974	NP_573076.1	RING	124..169	CDD:238093	35/44 (80%)
RNF5	NP_008844.1	PLN03208	21..>116	CDD:178747	58/94 (62%)
		RING-HC_RNF5	25..70	CDD:319657	34/44 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..110		17/30 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152551
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2074
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000717
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102074
Panther	1	1.100	-	-	O	PTHR12313
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	1	1.000	-	-		X682
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.680