Protein Alignment sordd1 and RNF4

DIOPT Version :10

• Sequence 1: NP_573076.1
• Gene: sordd1 / 32532
• FlyBaseID: FBgn0030693
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_002929.1
• Gene: RNF4 / 6047
• HGNCID: 10067
• Length: 190
• Species: Homo sapiens
• Alignment Length: 83
• Identity: 25/83 - (30%)
• Similarity: 35/83 - (42%)
• Gaps: 10/83 - (12%)

  Fly   103 TDTKANEKDKEKEHTADDSLYECNICLDTAKDAV------VSM-CGHLFCWPCLHQWLLTRPNRK 160
            |.|..|.:|:............|.||:|...:.|      ||. |||:||..||...|   .|..
Human   110 THTPRNARDEGATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSL---KNAN 171

  Fly   161 LCPVCKAAVDKDKVIPLY 178
            .||.|:..::..:..|:|
Human   172 TCPTCRKKINHKRYHPIY 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sordd1	NP_573076.1	RING-HC_RNF185	123..179	CDD:438402	21/63 (33%)
RNF4	NP_002929.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Required for ubiquitination activity. /evidence=ECO:0000250|UniProtKB:Q9QZS2	1..16
		Mediates interaction with TRPS1. /evidence=ECO:0000250|UniProtKB:Q9QZS2	4..61
		SUMO interaction motif 1. /evidence=ECO:0000269|PubMed:18408734	36..39
		SUMO interaction motif 2. /evidence=ECO:0000269|PubMed:18408734	46..49
		SUMO interaction motif 3. /evidence=ECO:0000269|PubMed:18408734	57..59
		SUMO interaction motif 4. /evidence=ECO:0000269|PubMed:18408734	67..70
		RING-HC_RNF4	127..183	CDD:438195	19/58 (33%)