DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8974 and TRIM39

DIOPT Version :9

Sequence 1:NP_573076.1 Gene:CG8974 / 32532 FlyBaseID:FBgn0030693 Length:277 Species:Drosophila melanogaster
Sequence 2:NP_067076.2 Gene:TRIM39 / 56658 HGNCID:10065 Length:518 Species:Homo sapiens


Alignment Length:42 Identity:16/42 - (38%)
Similarity:24/42 - (57%) Gaps:0/42 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 CNICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCPVCK 166
            |::||:..|:.|:..|||.||..|:.:|.........||||:
Human    29 CSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCR 70

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8974NP_573076.1 RING 124..169 CDD:238093 16/42 (38%)
TRIM39NP_067076.2 RAD18 20..>179 CDD:333230 16/42 (38%)
RING-HC_TRIM39_C-IV 26..69 CDD:319515 14/39 (36%)
RING-HC finger (C3HC4-type) 29..69 CDD:319515 14/39 (36%)
AtpF 175..352 CDD:333342
Interaction with CDKN1A. /evidence=ECO:0000269|PubMed:23213251 268..337
SPRY_PRY_TRIM39 335..513 CDD:293979
Interaction with CDKN1A. /evidence=ECO:0000269|PubMed:23213251 389..518
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R146
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

Return to query results.
Submit another query.