DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8974 and rnf5

DIOPT Version :9

Sequence 1:	NP_573076.1	Gene:	CG8974 / 32532	FlyBaseID:	FBgn0030693	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	XP_003200552.1	Gene:	rnf5 / 100537822	ZFINID:	ZDB-GENE-100805-3	Length:	205	Species:	Danio rerio

Alignment Length:	221	Identity:	109/221 - (49%)
Similarity:	137/221 - (61%)	Gaps:	34/221 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ASELKKSNT------SYSFTGDYLSGGNKADLKGGYPFGGTDTDTKANEKDKEKEHTADDSLYEC 125
            |:|.::|::      ...|.|   |||      |..|.||.:     .|:|:|:      :.:||
Zfish     3 AAEQQRSSSDGAAARGAGFPG---SGG------GAGPGGGAE-----GERDRER------ATFEC 47

  Fly   126 NICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCPVCKAAVDKDKVIPLYGRNSTHQEDPRN 190
            |||||||:|||:|:||||||||||||||.|||:|:.||||||.:.:|||||||||.|:.|||||.
Zfish    48 NICLDTARDAVISLCGHLFCWPCLHQWLETRPSRQQCPVCKAGISRDKVIPLYGRGSSSQEDPRL 112

  Fly   191 KVPPRPAGQRTEPDPVPGFPGFGFGDGFHMSFGIGAFPFGFITSTLNFGEPRPPA-ANRGTRQYE 254
            |.||||.|||:||:....|.||| ..|||||||||||||||.|:..|...|...| |:.|..|..
Zfish   113 KTPPRPQGQRSEPESRGPFQGFG-DTGFHMSFGIGAFPFGFFTTVFNTNNPFHRADAHYGADQQA 176

  Fly   255 DEQT------LSKLFSYLAVVWILWL 274
            :|..      ...||.:||:.:..|:
Zfish   177 NENANNGNNWQDSLFLFLAIFFFFWI 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8974	NP_573076.1	RING	124..169	CDD:238093	37/44 (84%)
rnf5	XP_003200552.1	PLN03208	45..>141	CDD:178747	68/96 (71%)
rnf5	XP_003200552.1	RING	46..91	CDD:238093	37/44 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000717
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102074
Panther	1	1.100	-	-	O	PTHR12313
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R146
SonicParanoid	1	1.000	-	-		X682
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.730