Protein Alignment Rhp and Pdcd6ip

DIOPT Version :9

• Sequence 1: NP_511168.3
• Gene: Rhp / 32531
• FlyBaseID: FBgn0026374
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: XP_006244059.1
• Gene: Pdcd6ip / 501083
• RGDID: 68357
• Length: 873
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 151/656 - (23%)
• Similarity: 252/656 - (38%)
• Gaps: 192/656 - (29%)

  Fly   127 LKETKEINFMEPFSDFILEHY---SEEPSMYIDAIADMTDTRQASKTPSRDALGVAL-------- 180
            ||:|.|::..:|...||.:.|   .||.:.|..|..:::..|       |.|||..|
  Rat     9 LKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLR-------RSALGRPLDKHEGALE 66

  Fly   181 -LFRYYNTLYYVERRFFPPDRNLGVYFEWYD-----SLTG--VPSCQRTIAFEKACTLFNLGGIY 237
             |.|||:.:..:|.:|...:..:.:.|.|.|     ||.|  |.....::.:||:|.|||...:.
  Rat    67 TLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALA 131

  Fly   238 TQIGARHDRTTERGLDLAVDSFLRAAGVFRHIYDTFTNA----PSMDLKPQVLDVLVSLMLSQAR 298
            :||.|..:...:.||..|...:..|:|.|.||.||..:|    |::|:.|..:..|..:||:||:
  Rat   132 SQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIMLAQAQ 196

  Fly   299 ECLFEKLQLQIEAMSHDCQAFRD------LAGEAAQISHEYNEMHKNIQANDT---HTYLPECWA 354
            |..|.|             |.||      :|..|.|.:..:.:..|..|..|.   :.|..|.:.
  Rat   197 EVFFLK-------------ATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDALPKYFYFQEVFP 248

  Fly   355 GLVPVKAELYKAFAHFYKARSIDATDELKASKSSQKNQESFIGNSQEVERITTADYGASDEASTS 419
            .|. .|..:.:|.|.::  :||.|           |.|:.|               |
  Rat   249 TLA-AKQCIMQANAEYH--QSILA-----------KQQKKF---------------G-------- 276

  Fly   420 IANKLAHLKEALASIEEAQRLQRMCRFLKNKASLTEVMKEVHSKSQEELEKF-RLQASAKNIEDG 483
                           ||..|||.....:||.||..:....|...|    :|. |..|:||  :|.
  Rat   277 ---------------EEIARLQHAAELIKNVASRYDEYVNVKDFS----DKINRALAAAK--KDN 320

  Fly   484 DLLE-------RSVEASSKFTLSLTGPDFT--SHKVKDPFKRLGPI------AIFSARRHWTAPR 533
            |.:.       :.::...|.||....|...  |.|..|.|:::.|:      |:||.|:.....|
  Rat   321 DFIYHDRVPDLKDLDPIGKATLVKPTPVNVPISQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNR 385

  Fly   534 CV-RLQKGSSLYHSVPSNDNKCPLDNDDDEEHDGGYNLYKEEFENFGFHVRGDAPVIIAHVEINS 597
            .: ::::.::|.:.|.::.| .|...:|                     |.||........:..:
  Rat   386 SIAQMREATTLANGVLASLN-LPAAIED---------------------VSGDTVPQSILTKSTA 428

  Fly   598 LADLGGIKEGDFIVEIAGVDVKWYSHQQVVQLIQSCGSTLE--LRVI------------------ 642
            :.:.|||:..|.::            :::.:|:|.....||  ||::
  Rat   429 VVEQGGIQTVDQLI------------KELPELLQRNREILEESLRLLDEEEATDNDLRAKFKDRW 481

  Fly   643 --TPMDRNYLKPLSSKGS--LSTLSAA--SSSGISSGFPS---PTSIAAKPKLHLKTS-SSSRPA 697
              ||.:..| |||.::|:  .:.|..|  :...:...:.|   ..::..||:..|..: .|:.||
  Rat   482 QRTPSNDLY-KPLRAEGAKFRAVLDKAVQADGQVKERYQSHRDTIALLCKPEPELNAAIPSANPA 545

  Fly   698 GSVSSS 703
            .::..|
  Rat   546 KTMQGS 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhp	NP_511168.3	HR1_Rhophilin-1	34..118	CDD:212023
		BRO1_Rhophilin	122..514	CDD:185767	109/428 (25%)
		PDZ_signaling	570..642	CDD:238492	13/73 (18%)
Pdcd6ip	XP_006244059.1	BRO1_Alix	2..350	CDD:185763	106/418 (25%)
		V_Alix	365..703	CDD:185748	41/222 (18%)
		Amelogenin	<819..>873	CDD:197891

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2220
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810