Protein Alignment Rhp and mop

DIOPT Version :9

• Sequence 1: NP_511168.3
• Gene: Rhp / 32531
• FlyBaseID: FBgn0026374
• Length: 718
• Species: Drosophila melanogaster
• Sequence 2: NP_648722.2
• Gene: mop / 39610
• FlyBaseID: FBgn0036448
• Length: 1833
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 126/622 - (20%)
• Similarity: 218/622 - (35%)
• Gaps: 137/622 - (22%)

  Fly   122 MIPLGLKETKEINFMEPFSDFILEHYSEEPSMYIDAIADMTDTRQASKTPSRDALGVALLFRYYN 186
            |:...||.:.|.........:|.|.|.|:|..|...:..:...|..:...::|  |..::.|||.
  Fly     9 MLWFALKSSPEGTSFAALKKYIAEFYHEDPEAYSKEVHALETLRNQAMHTTKD--GAPVMKRYYC 71

  Fly   187 TLYYVERRFFPPDRNLGVY-FEWYDSLTGVPSCQRTIAFEKACTLFNLGGIYTQIGARHDRTTER 250
            .|:.::.| ||...:.|:: |:|.|...........:.||:|..|||:..::||.||...|....
  Fly    72 QLHALQNR-FPQLADRGIFTFKWKDLYHSAVHEVTDLRFERAAVLFNIAALHTQSGASVTRGDVD 135

  Fly   251 GLDLAVDSFLRAAGVFRHIYDTFTNAPSMD--LKPQVLDVLVSLMLSQARECLFEKLQLQIEAMS 313
            |:.:|...|..||..:..:.:.:.|.....  :.|::|.....:..:||:||:.||..:
  Fly   136 GMKMACTHFQAAAWAYGELRERYANVNGGGDFMTPELLVFQQQVCFAQAQECILEKSLI------ 194

  Fly   314 HDCQAFRDLAGEAAQISHEYNEMHKNI----------QANDTHTYLPECWAGLVPVKAELYKAFA 368
             |.:....:|...|||...|......:          |..|:..|  :.|...|..|........
  Fly   195 -DNRKPHIVAKVTAQIVVYYGAALAALLTGGDDGPVAQVIDSSVY--KLWKKYVRFKINYLTCIL 256

  Fly   369 HFYKARSIDATDELKASKSSQKNQESFIGNSQEVERIT--TADYGASDEA---STSIANKLAHLK 428
            :.|:.:           .|.:|.|..        ||:|  .|.:...:||   |..:.:: ..:.
  Fly   257 YLYQGQ-----------HSEEKRQMG--------ERVTLYQASWDKLEEARKESKGLPDQ-REIN 301

  Fly   429 EAL---ASIEEAQRLQRMCRFLKNKASLTEVMKEVHSKSQEELEKFRLQASAKNIEDGDLLERSV 490
            |:|   |.:.||:|        ||..:..|.   ::.::..||........| |:.:|...:.|.
  Fly   302 ESLSFTADVVEAKR--------KNAKNENEF---IYHEAVPELSTIAAVQGA-NLVNGIGFQVSD 354

  Fly   491 EASSKFTLSLTGPDFTSHKVKDPFKRLGPIAIFSARRHWTAPRCVRLQKGSSLYHSVPSNDNKCP 555
            |..:       |||.        |.||.|:....|...::..:...|:|..:|.
  Fly   355 EEHA-------GPDI--------FARLVPMKAHEASSLYSEEKAKLLRKYGALL----------- 393

  Fly   556 LDNDDDEEHDGGYNLYKEEFENFGFHVRGDAPVIIAHVEINSLADLGGIKEGDFIVEIAGVDVKW 620
                  ||.|.....|.........::..:....:....::..|.|...|..
  Fly   394 ------EEKDTQLESYMSSLTLDNLNINEEQANKLPQGIVDRCAALNANKTA------------- 439

  Fly   621 YSHQQVVQLIQSCGSTLELRVITPMDRNYLKPLSSKGSLSTLSAASSSGISSGFPSPTSIAAKPK 685
                 :..|:::.....|  :...::.|.       |.:|::..|.:.. ...|.|.|.:...|.
  Fly   440 -----ISDLVEAMSQLAE--ITADVETNL-------GEISSMLEAEAKA-EREFQSATGVQRTPN 489

  Fly   686 LHL--------KTSSSSRPAGSVSSSSWNPFRRTPSL 714
            .|:        |.|.:...||    .|.|..|:..||
  Fly   490 AHITELSREFQKYSEAHARAG----ESNNTLRKAMSL 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhp	NP_511168.3	HR1_Rhophilin-1	34..118	CDD:212023
		BRO1_Rhophilin	122..514	CDD:185767	91/412 (22%)
		PDZ_signaling	570..642	CDD:238492	6/71 (8%)
mop	NP_648722.2	BRO1_HD-PTP_like	2..363	CDD:185762	91/412 (22%)
		V_HD-PTP_like	368..702	CDD:185747	32/204 (16%)
		ALIX_LYPXL_bnd	421..699	CDD:290660	23/134 (17%)
		Med15	808..>1246	CDD:255446
		Y_phosphatase	1558..1788	CDD:278528
		PTPc	1559..1745	CDD:238006

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2220
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810