DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS30 and Mrps30

DIOPT Version :9

Sequence 1:	NP_001285297.1	Gene:	mRpS30 / 32530	FlyBaseID:	FBgn0030692	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_067531.1	Gene:	Mrps30 / 59054	MGIID:	1926237	Length:	442	Species:	Mus musculus

Alignment Length:	489	Identity:	125/489 - (25%)
Similarity:	189/489 - (38%)	Gaps:	126/489 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GQSQLQLNSTDAEPAYPEIQDLSF-------------------KARKQKDAANWHEEIRQVPTVE 65
            |:...|..:..|....||::||..                   ||.:|:....|...:...|:|:
Mouse    13 GRGLSQNAAAKASATAPEVRDLEVVATPVARYPPIVASMTADSKAARQRRVQRWQATVHAAPSVD 77

  Fly    66 EK---MIKINMPRYYGFKVVDFNDSKIPYNALPLTQHYTRTV-LEDLPSETDKKAQAKDSEQEQE 126
            ||   :.|:...:|    ||....|.:  ||....|.:|:|| :..||     .|.|    ....
Mouse    78 EKIRILTKMQFKKY----VVHPQISAL--NADRWYQSFTKTVFVSGLP-----PAPA----LSPP 127

  Fly   127 QPSVDGLFKAARGDVIDALEFAHDYYKHLEKQHNSAESNP---VERERILTQIIVEQLNRALLQS 188
            .||:|  ..|.|..|.|.:         |::|.......|   .:|.:.|...|::|:.|.|:..
Mouse   128 PPSLD--LAALRAAVCDCI---------LQEQVYVRRRRPRSLFDRRQALASSILDQVVRTLVNL 181

  Fly   189 LSEEYKHLDELDVDYNPRHEAFWAVGGVDPPKNVQKSKKGREWQKDMANESVDRMVQYTGAPYLA 253
            |:.....|....:|.....:.:|..|....|..   .:||.          :|           |
Mouse   182 LAPLNPVLSTAALDCKRSVDFYWLRGEERIPAG---HRKGH----------ID-----------A 222

  Fly   254 LRHRKQLTPWKTEAESENLELSKQLPRFKHDPRTLGYSTKHQHATNVP---------GYWPKGNE 309
            ||::....|      ...:.:|||||.|.    .|.||.    .|.:|         ..:.:..|
Mouse   223 LRYQINDKP------HNQIRISKQLPEFV----PLDYSI----PTEIPVMKCKPDKLPLFRRQYE 273

  Fly   310 NN------------FGLLSFQSRAHL---QIRPKSFGEQDQLEALHSL----AIKSSYAWLLAQA 355
            |:            :|...|    ||   :::.:....|:|.|.:.::    ||.|.:||..|||
Mouse   274 NSIFTGSKTADPCCYGHTQF----HLIPDRLKRERLIRQNQAEQVEAVFRANAIASLFAWTGAQA 334

  Fly   356 NYNGFNTYNELTYPMNTQTVITNGREWSFYEYQLNTLLLHGTNVAENPRVNFCRGTKPLPLYAEI 420
            .|.||.:..::|.|..:|.|||:|:.:||:.||||||.|.......|||.|.|.|::..||| |.
Mouse   335 MYQGFWSEADVTRPFVSQAVITDGKYFSFFCYQLNTLALTVQADQNNPRKNLCWGSQSQPLY-ET 398

  Fly   421 SASGKCVDFNDNALRHLLNFYANAPSIQRSIGEQ 454
            ........|:|..|..:::|..|.|   |..|.|
Mouse   399 VEDNDVKGFDDGTLLQIVHFLLNKP---REDGAQ 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS30	NP_001285297.1	PDCD9	6..442	CDD:284543	120/475 (25%)
Mrps30	NP_067531.1	PDCD9	1..420	CDD:284543	120/475 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830620
Domainoid	1	1.000	84	1.000	Domainoid score	I8295
eggNOG	1	0.900	-	-		E1_KOG4461
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9607
Inparanoid	1	1.050	84	1.000	Inparanoid score	I5170
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006311
OrthoInspector	1	1.000	-	-		oto94327
orthoMCL	1	0.900	-	-		OOG6_108555
Panther	1	1.100	-	-	LDO	PTHR13014
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3573
SonicParanoid	1	1.000	-	-		X5259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.780