DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Paf-AHalpha and pafah1b2

DIOPT Version :9

Sequence 1:	NP_525089.2	Gene:	Paf-AHalpha / 32529	FlyBaseID:	FBgn0025809	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001076320.1	Gene:	pafah1b2 / 567170	ZFINID:	ZDB-GENE-060526-43	Length:	228	Species:	Danio rerio

Alignment Length:	224	Identity:	94/224 - (41%)
Similarity:	143/224 - (63%)	Gaps:	7/224 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NPCVLPTPLPDLDGDKRWHSIHRRFISDCREKDPDVIFLGDCIFETVQDTEAWNKYFAPLHCLNF 66
            ||...|.|:.|:.||.||.|.|.||:.:|::.:|||:|:||.:.:.:|..|.|.:.|:|||.|||
Zfish     6 NPAAEPAPVTDVQGDGRWMSQHNRFVQECKDAEPDVLFVGDSMVQLMQQYEVWRELFSPLHALNF 70

  Fly    67 SIRDDCTEHVLWRIENGALDNVNPKIVVLHVGTNNVRNSAEEVAEGVLANVTKIRQKLPNAYIVL 131
            .|..|.|.:|:||::||.|:|:.|::||:.|||||..::|::||.|:||....:..:||.:.:::
Zfish    71 GIGGDTTSNVMWRLQNGELENIRPRVVVVWVGTNNHEHTADQVAGGILAIAQLLLSRLPKSKMIV 135

  Fly   132 PSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVAIDKGLVQTDGSISHHDMFDYKNLTNAG 196
            ..|||||:.||.||||||.:|.::......|..:|.:.:....|.:||:||..|||||.:||.:.
Zfish   136 LGLLPRGEFPNPLREKNASVNNLLRASLPRLGPIQFLDMGSSFVHSDGTISSRDMFDYLHLTASA 200

  Fly   197 AKKILEPLYDLLSQILNENEPENDLTPSE 225
            .:.|...|::||.|:|.|       ||.|
Zfish   201 YRTISTTLHELLLQLLEE-------TPQE 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Paf-AHalpha	NP_525089.2	PAF_acetylesterase_like	3..212	CDD:238858	88/208 (42%)
pafah1b2	NP_001076320.1	PAF_acetylesterase_like	7..202	CDD:238858	83/194 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589989
Domainoid	1	1.000	140	1.000	Domainoid score	I4706
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1932
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3504
OMA	1	1.010	-	-		QHG48396
OrthoDB	1	1.010	-	-		D1604899at2759
OrthoFinder	1	1.000	-	-		FOG0004246
OrthoInspector	1	1.000	-	-		otm24869
orthoMCL	1	0.900	-	-		OOG6_104898
Panther	1	1.100	-	-	LDO	PTHR11852
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4710
SonicParanoid	1	1.000	-	-		X2985
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940