Protein Alignment Paf-AHalpha and Megf8

DIOPT Version :9

• Sequence 1: NP_525089.2
• Gene: Paf-AHalpha / 32529
• FlyBaseID: FBgn0025809
• Length: 225
• Species: Drosophila melanogaster
• Sequence 2: NP_001153872.1
• Gene: Megf8 / 269878
• MGIID: 2446294
• Length: 2789
• Species: Mus musculus
• Alignment Length: 87
• Identity: 18/87 - (20%)
• Similarity: 28/87 - (32%)
• Gaps: 40/87 - (45%)

  Fly    28 SDCREKDPDVIFLGDCIFETVQDTEA-----------------WNKYFAPLHCLNFSIRDDCTEH 75
            :|||....:|.:.|:|       :||                 |.:.|.         |...|..
Mouse  1920 NDCRINQREVFWAGNC-------SEAACGAADCEQCTREGKCMWTRQFK---------RTGETRR 1968

  Fly    76 VL-------WRIENGALDNVNP 90
            :|       |...:.:|.||:|
Mouse  1969 ILSVQPTYDWTCFSHSLLNVSP 1990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Paf-AHalpha	NP_525089.2	PAF_acetylesterase_like	3..212	CDD:238858	18/87 (21%)
Megf8	NP_001153872.1	CUB	49..139	CDD:238001
		PLN02153	203..484	CDD:177814
		Kelch_4	227..276	CDD:290154
		KELCH repeat	228..275	CDD:276965
		Kelch 1	241..287
		KELCH repeat	279..331	CDD:276965
		Kelch 2	290..338
		Kelch 3	346..399
		Kelch 4	402..453
		KELCH repeat	448..510	CDD:276965
		Kelch 5	459..511
		Kelch 6	525..575
		PSI	950..998	CDD:279745
		vWFA	1011..>1035	CDD:294047
		EGF_3	1078..1112	CDD:289699
		EGF_Lam	1210..1259	CDD:238012
		Kelch 7	1522..1570
		PLN02153	<1540..1763	CDD:177814
		KELCH repeat	1566..1612	CDD:276965
		Kelch 8	1580..1629
		KELCH repeat	1621..1668	CDD:276965
		Kelch_3	1630..1680	CDD:290151
		Kelch 9	1632..1679
		KELCH repeat	1673..1721	CDD:276965
		Kelch 10	1685..1735
		Kelch_6	1728..1775	CDD:290672
		KELCH repeat	1729..1773	CDD:276965
		Kelch 11	1740..1787
		Kelch 12	1796..1841
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2468..2508
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2762..2789

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900