DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Paf-AHalpha and Ice1

DIOPT Version :9

Sequence 1:	NP_525089.2	Gene:	Paf-AHalpha / 32529	FlyBaseID:	FBgn0025809	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_659086.2	Gene:	Ice1 / 218333	MGIID:	2385865	Length:	2241	Species:	Mus musculus

Alignment Length:	184	Identity:	43/184 - (23%)
Similarity:	58/184 - (31%)	Gaps:	51/184 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 NKYFAPLHCLNFSI----------RDDCTEHVLWRIENGAL----DNVNPKIVVLHVGTNNVRNS 105
            |:|...|..|...|          :..|.|....|.||..|    :.:..||..|......:.:.
Mouse    30 NEYVEALIALKQKIINTDNLLTEYQKKCDELQFARRENSTLHHQVEQMLQKISPLQKCQEELGSL 94

  Fly   106 AEEVAEGVLANVTKIRQKLPNAYI-VLPSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVA 169
            ..|:.|  ..:..|:.|.....|. |....|....|..||..|..|:.|.
Mouse    95 KAELEE--KKSSLKLYQDTHQEYARVKEECLRTDAQKKKLEAKVKKLEEA--------------- 142

  Fly   170 IDKGLVQTDGSISHHDMFDYKNLTNAGAKKILEPLYDLLSQILNE-----NEPE 218
               .:.||.         |:|.|.|  .|||||..:....:.|:|     ||.|
Mouse   143 ---AVKQTQ---------DFKQLRN--EKKILEKEFKKTQERLDEFSKQKNEKE 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Paf-AHalpha	NP_525089.2	PAF_acetylesterase_like	3..212	CDD:238858	38/171 (22%)
Ice1	NP_659086.2	DUF2031	<26..>180	CDD:299055	40/180 (22%)
		DUF4201	53..185	CDD:290581	38/161 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	222..255
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	273..315
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	368..387
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	552..590
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	703..817
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	971..1119
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1231..1328
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1419..1475
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1543..1671
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1777..1800
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1812..1843
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930