DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Paf-AHalpha and Pafah1b3

DIOPT Version :9

Sequence 1:	NP_525089.2	Gene:	Paf-AHalpha / 32529	FlyBaseID:	FBgn0025809	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001344279.1	Gene:	Pafah1b3 / 18476	MGIID:	108414	Length:	232	Species:	Mus musculus

Alignment Length:	215	Identity:	98/215 - (45%)
Similarity:	144/215 - (66%)	Gaps:	0/215 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NPCVLPTPLPDLDGDKRWHSIHRRFISDCREKDPDVIFLGDCIFETVQDTEAWNKYFAPLHCLNF 66
            ||...|||:.|:.||.||.|:|.||::|.::|:|:|:|:||.:.:.:...|.|.:.|:|||.|||
Mouse     7 NPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNF 71

  Fly    67 SIRDDCTEHVLWRIENGALDNVNPKIVVLHVGTNNVRNSAEEVAEGVLANVTKIRQKLPNAYIVL 131
            .|..|.|:|||||:|||.|:::.|||||:.|||||..::||:|..|:.|.|..:.:..|.|.:|:
Mouse    72 GIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKAIVQLVNKLQPQARVVV 136

  Fly   132 PSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVAIDKGLVQTDGSISHHDMFDYKNLTNAG 196
            ..||||||.||.|||||.::||:|.....|..|...:..|.|.|.:||:||||||:||.:|:..|
Mouse   137 LGLLPRGQHPNPLREKNRQVNELVRAALAGYPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLG 201

  Fly   197 AKKILEPLYDLLSQILNENE 216
            ...:...|:.||.::|.:::
Mouse   202 YTPVCRALHSLLLRLLAQDQ 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Paf-AHalpha	NP_525089.2	PAF_acetylesterase_like	3..212	CDD:238858	96/208 (46%)
Pafah1b3	NP_001344279.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		6/12 (50%)
Pafah1b3	NP_001344279.1	PAF_acetylesterase_like	8..206	CDD:238858	93/197 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845422
Domainoid	1	1.000	145	1.000	Domainoid score	I4555
eggNOG	1	0.900	-	-		E1_KOG1388
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	230	1.000	Inparanoid score	I3436
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48396
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004246
OrthoInspector	1	1.000	-	-		otm43043
orthoMCL	1	0.900	-	-		OOG6_104898
Panther	1	1.100	-	-	O	PTHR11852
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2985
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.760