DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Paf-AHalpha and pafah1b2

DIOPT Version :9

Sequence 1:	NP_525089.2	Gene:	Paf-AHalpha / 32529	FlyBaseID:	FBgn0025809	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	XP_004916134.1	Gene:	pafah1b2 / 100492775	XenbaseID:	XB-GENE-962580	Length:	259	Species:	Xenopus tropicalis

Alignment Length:	221	Identity:	107/221 - (48%)
Similarity:	148/221 - (66%)	Gaps:	0/221 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NPCVLPTPLPDLDGDKRWHSIHRRFISDCREKDPDVIFLGDCIFETVQDTEAWNKYFAPLHCLNF 66
            |...:|....||.||.||.|.|.||:.||::|:|||:|:||.:.:.:|..|.|.:.|:|||.|||
Frog    37 NSAAVPLAAEDLQGDDRWLSQHNRFVLDCKDKEPDVLFVGDSLVQLMQQYEIWRELFSPLHALNF 101

  Fly    67 SIRDDCTEHVLWRIENGALDNVNPKIVVLHVGTNNVRNSAEEVAEGVLANVTKIRQKLPNAYIVL 131
            .|..|.|.|||||::||.|:|:.||::||.:||||..|||||||.||.|.:..|....|.|.|::
Frog   102 GIGGDTTRHVLWRLQNGELENIKPKVIVLWIGTNNHENSAEEVAGGVEAIINVINILQPQAKIIV 166

  Fly   132 PSLLPRGQQPNKLREKNAKINEVVNGLTKGLYRVQTVAIDKGLVQTDGSISHHDMFDYKNLTNAG 196
            .:|||||::||.||||||::|.::......|..||.:.:|.|.|.:||:||.|||||:.:||.||
Frog   167 MALLPRGEKPNPLREKNARVNHILRSWLPRLPGVQLLDVDNGFVHSDGTISRHDMFDFLHLTAAG 231

  Fly   197 AKKILEPLYDLLSQILNENEPENDLT 222
            ..|:..||::|:.|:|.|...|..:|
Frog   232 YAKVCRPLHELIMQLLEETPEEKQVT 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Paf-AHalpha	NP_525089.2	PAF_acetylesterase_like	3..212	CDD:238858	102/208 (49%)
pafah1b2	XP_004916134.1	PAF_acetylesterase_like	39..247	CDD:238858	102/207 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	147	1.000	Domainoid score	I4470
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1932
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3357
OMA	1	1.010	-	-		QHG48396
OrthoDB	1	1.010	-	-		D1604899at2759
OrthoFinder	1	1.000	-	-		FOG0004246
OrthoInspector	1	1.000	-	-		otm48167
Panther	1	1.100	-	-	LDO	PTHR11852
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4710
SonicParanoid	1	1.000	-	-		X2985
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110