Protein Alignment Efhc1.1 and efhc1

DIOPT Version :10

• Sequence 1: NP_573075.1
• Gene: Efhc1.1 / 32528
• FlyBaseID: FBgn0030691
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_001008106.1
• Gene: efhc1 / 493468
• XenbaseID: XB-GENE-1011237
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 194/563 - (34%)
• Similarity: 293/563 - (52%)
• Gaps: 65/563 - (11%)

  Fly     4 IPGMPLLPGTLFRDVSKGHYPKPQSLANVQGLSMLSDRQQPAPVESGSVTVDISCPPVGASSI-- 66
            :.|:|.|||..:||.:|..:.:.|:|....|.|        .|:   ..||.|...|:.|:.:
 Frog     6 VHGLPFLPGNTYRDPTKSAFHRSQTLTYKNGYS--------RPI---LPTVGIGREPITANQLSQ 59

  Fly    67 ------------------YPPRSGPRMPPWLAYDKKVLCFHAYFKQTLQEVYHAPYLVRKVKIYY 113
                              .|......:|.::|:|||||.|..||::|:.......|.||:|.:||
 Frog    60 AELDELANKRPTLTYGRAKPAPPSDFIPSYVAFDKKVLRFEGYFQETVPLSPEEHYRVRRVTLYY 124

  Fly   114 YLEDGTLEIYEPRVDNSGIVQGCVVHRQRVQKAPPCDNEFMSLIDLNVDQTVQIFDRQYHITDCD 178
            ||||.|:.:.||.::||||.||..:.|||..|....|.....  ||||...|.::.|.:.:..||
 Frog   125 YLEDDTISVIEPPMENSGIPQGTFIKRQRHPKNANGDPYHWK--DLNVGINVTLYGRTFRLISCD 187

  Fly   179 PFTRTFLNKRGITVPDPVKSPCDPTEEQRKRENQPRSGNLIPKN-HPFAQFLKYDRQILKFQAYW 242
            .||:.||...||.:..|...|.||..|.|:|.|:.   .:.|.: ....|:|..||::|:|.|.|
 Frog   188 SFTQEFLESEGIELNPPEGIPTDPFTELRRRPNRT---FVTPSDFDKLKQYLTMDRKVLRFFAVW 249

  Fly   243 DDRTE--FGDVRKLELCYYLSDDTIEIKEQHIRNSGRDGPTVFLKRGRLAREFEGLQLPGQMTPM 305
            || ||  ||:...:.:.|||||||:||:|.|.||.|||...|.:||..|.:
 Frog   250 DD-TESMFGEKHPVLIHYYLSDDTVEIREVHERNDGRDPFPVLMKRQHLPK-------------- 299

  Fly   306 TLLNVLGTNMRNVRYCVDPLNTGNKEI-HYYREKDLQIGSVINVYGRAVVITELDPFTQNYYRQR 369
                |:.........||  |...::|: .::...|.::|..|::.||...|.:.|.:|:::||.:
 Frog   300 ----VVNDTKDTFPMCV--LEISDQEVKEWFSPGDFKVGKHISILGRKFFIYDCDAYTRDFYRDK 358

  Fly   370 YGIQDFTPLPIPARSDDCADHRSERQLPPYNGWGSYEDSVGNCISVEPKPPKSDFKKFIKYDRYV 434
            .||.|..|:.:....:| .:.:..:::|||||:|..|||:.||:|:.|||||.|..|.::.|..|
 Frog   359 MGIGDLQPVEVNKERED-EEEKVIQEIPPYNGFGLLEDSLQNCLSLVPKPPKKDVLKMLENDHNV 422

  Fly   435 LRFGAKMLSTIKANCERIFVISYYLCDDTLQIQEIAVRNSGFLGGEFMKRTRLELPGQERFSCKQ 499
            ||:...:.|....:..|.||:||:|.:|.|.|.|..|||||.:||:|::::|:.:||.   :...
 Frog   423 LRYVVILDSPNPEDKVRRFVLSYFLANDMLSIFERQVRNSGIIGGKFLEKSRVLVPGS---TVDN 484

  Fly   500 PQYYMPWNFFVGSTMSLKDFIFHIVSADEYTLMYMEHHPEIFP 542
            |.||.|.:|.:|:.:.:.:..|.|..||||.|.||:.|.:.||
 Frog   485 PIYYGPKDFTIGAAIEVFNHRFIITDADEYVLNYMKAHSKEFP 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Efhc1.1	NP_573075.1	DM10	82..189	CDD:128921	45/106 (42%)
		DM10	232..370	CDD:128921	47/140 (34%)
		DM10_dom	424..530	CDD:461948	38/105 (36%)
efhc1	NP_001008106.1	DM10_dom	86..190	CDD:461948	43/105 (41%)
		DM10_dom	232..351	CDD:461948	46/139 (33%)
		DM10_dom	414..515	CDD:461948	38/103 (37%)